Technology Process of 2H-Pyran-2-one, tetrahydro-3-(phenylmethyl)-6-(2-propynylidene)-, (E)-
There total 9 articles about 2H-Pyran-2-one, tetrahydro-3-(phenylmethyl)-6-(2-propynylidene)-, (E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium cyanide; silver nitrate;
In
ethanol; water;
at 0 ℃;
for 0.5h;
in the dark;
DOI:10.1021/ja00278a038
- Guidance literature:
-
With
triethylamine;
copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride;
at 35 ℃;
Yield given;
DOI:10.1021/ja00334a068
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 60 percent / pyridinium dichromate / dimethylformamide / 24 h / in the dark
2: 88 percent / 1,1-carbonyldiimidazole, pyridine / tetrahydrofuran / 48 h / Ambient temperature
3: 75 percent / diisopropylamine, n-butyllithium / tetrahydrofuran / 48 h / Ambient temperature
4: 73 percent / N-iodosuccinimide, NaHCO3, tetrabutylammonium hydroxide / CH2Cl2; H2O / 0.5 h
5: 91 percent / PdCl2(Ph3P)2, CuI, Et3N
6: 71 percent / AgNO3, KCN / ethanol; H2O / 0.5 h / 0 °C / in the dark
With
pyridine; potassium cyanide; bis-triphenylphosphine-palladium(II) chloride; N-iodo-succinimide; copper(l) iodide; dipyridinium dichromate; n-butyllithium; tetra(n-butyl)ammonium hydroxide; sodium hydrogencarbonate; silver nitrate; triethylamine; diisopropylamine; 1,1'-carbonyldiimidazole;
In
tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ja00278a038
