Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester

Base Information

• Chemical Name: Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester
• CAS No.: 936494-86-9
• Molecular Formula: C₃₂H₄₂Br₂N₂O₉
• Molecular Weight: 758.501
• Mol file: 936494-86-9.mol

Synonyms:

Chemical Property of Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester

There total 1 articles about Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromophenyl isocyanate (2493-02-9) + C54H88O14 → acetic acid 3-acetoxy-5-(4-bromo-phenylcarbamoyloxy)-1-[3-(4,6-dimethyl-2,8-dioxa-bicyclo[3.2.1]oct-3-yl)-1-methyl-propyl]-2-methyl-pentyl ester + acetic acid 1-[2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester + C22H26Br2N2O5 + Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester (936494-86-9)

Guidance literature:

Multistep reaction;

DOI:10.1016/j.tet.2007.02.011

Reference yield:

Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester (936494-86-9) → C28H38Br2N2O7

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 23h;

DOI:10.1016/j.tet.2007.02.011

Reference yield:

2,2-dimethoxy-propane (77-76-9) + Acetic acid (1R,2R,5S,6R)-1-[(1R,2R)-2-acetoxy-4-(4-bromo-phenylcarbamoyloxy)-1-methyl-butyl]-6-(4-bromo-phenylcarbamoyloxy)-5-methoxy-2-methyl-heptyl ester (936494-86-9) → C31H42Br2N2O7

Guidance literature:

With methanol; camphor-10-sulfonic acid; potassium carbonate; Yield given. Multistep reaction; 1.) RT, 2.) acetone, 0 deg C;

DOI:10.1021/ja00095a071

upstream raw materials:

4-bromophenyl isocyanate