(4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Base Information

Chemical Name:(4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester
CAS No.:137143-93-2
Molecular Formula:C₃₉H₄₉N₃O₅
Molecular Weight:639.835
Hs Code.:

(4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Synonyms:

Suppliers and Price of (4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

There total 9 articles about (4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 129253-02-7
(2S,3S)-2-amino-N-benzyl-3-methylpentanamide

: 137143-92-1
(4S,5R)-4-Benzyl-5-((1R,2R)-2-carboxy-cyclopentyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

: 137143-93-2
(4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: With propylphosphonic anhydride; triethylamine; In N,N-dimethyl-formamide;

Reference yield:

: 59830-60-3
benzyl (1S)-(1-formyl-2-phenylethyl)carbamate

: 137143-93-2
(4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 1) n-BuLi, N,N,N',N'-tetramethylethylenediamine, Ti(O-iPr)4 / 1) ether, -78 deg C, 0.5 h, 2a) -78 deg C, 0.5 h, 2b) to 0 deg C

3: LiOH / tetrahydrofuran; methanol

4: 59 percent / Et₃N, propanephosphonic acid anhydride (PPA) / dimethylformamide

With titanium(IV) isopropylate; lithium hydroxide; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; propylphosphonic anhydride; triethylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

Reference yield:

: 130466-41-0
((1S,2R)-1-Benzyl-2-{(R)-2-[1-diisopropylcarbamoyloxy-meth-(Z)-ylidene]-cyclopentyl}-2-hydroxy-ethyl)-carbamic acid benzyl ester

: 137143-93-2
(4S,5R)-4-Benzyl-5-[(1R,2R)-2-((1S,2S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-cyclopentyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: LiOH / tetrahydrofuran; methanol

3: 59 percent / Et₃N, propanephosphonic acid anhydride (PPA) / dimethylformamide

With lithium hydroxide; propylphosphonic anhydride; triethylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;