(S)-4-morpholine

Base Information

Chemical Name:(S)-4-morpholine
CAS No.:220648-66-8
Molecular Formula:C₂₁H₂₂N₂O₄
Molecular Weight:366.417
Hs Code.:

(S)-4-<N-(benzyloxycarbonyl)indoline-2-carbonyl>morpholine

Synonyms:

Suppliers and Price of (S)-4-morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-4-morpholine

Chemical Property:

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Technology Process of (S)-4-morpholine

There total 3 articles about (S)-4-morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79815-20-6,78348-24-0
(S)-indoline-2-carboxylic acid

: 220648-66-8
(S)-4-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / NaHCO₃ / H₂O; toluene / Ambient temperature

2: 1.) N,N'-dicyclohexylcarbodiimide / 1.) CH₂Cl₂, 0 deg C, 30 min, 2.) CH₂Cl₂, from 0 deg C to RT, overnight

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In water; toluene;
DOI:10.1016/S0957-4166(98)00446-7

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 220648-66-8
(S)-4-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / NaHCO₃ / H₂O; toluene / Ambient temperature

2: 1.) N,N'-dicyclohexylcarbodiimide / 1.) CH₂Cl₂, 0 deg C, 30 min, 2.) CH₂Cl₂, from 0 deg C to RT, overnight

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In water; toluene;
DOI:10.1016/S0957-4166(98)00446-7

Reference yield:

: 110-91-8,99108-56-2
morpholine

: 104261-79-2
(S)-1-(benzyloxycarbonyl)indoline-2-carboxylic acid

: 220648-66-8
(S)-4-morpholine

Guidance literature:: With dicyclohexyl-carbodiimide; Yield given; Multistep reaction; 1.) CH₂Cl₂, 0 deg C, 30 min, 2.) CH₂Cl₂, from 0 deg C to RT, overnight;
DOI:10.1016/S0957-4166(98)00446-7