trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate

Base Information

• Chemical Name: trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate
• CAS No.: 57405-08-0
• Molecular Formula: C₃₄H₂₂O₄
• Molecular Weight: 494.546
• Mol file: 57405-08-0.mol

Synonyms:

Chemical Property of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate

Chemical Property:

• Storage Temp.: -20°C Freezer
• Solubility.: Benzene, Chloroform, Tetrahydrofuran

Purity/Quality:

trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyreneDibenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Protected trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (D452280), a metabolite of Benzopyrene (B205800). A carcinogen.

Technology Process of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate

There total 5 articles about trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene Dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

C34H23BrO4 (57405-01-3,61505-22-4) → (+/-)-trans-7,8-Dihydrobenzopyrene-7,8-diol dibenzoate (57405-08-0,62654-79-9,63268-37-1,63268-38-2,64912-51-2)

Guidance literature:

In xylene;

Reference yield:

9,10-dihydro benzopyrene (17573-15-8) → (+/-)-trans-7,8-Dihydrobenzopyrene-7,8-diol dibenzoate (57405-08-0,62654-79-9,63268-37-1,63268-38-2,64912-51-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 60 percent / I₂

2: 57 percent / NBS

3: 50 percent / xylene

With N-Bromosuccinimide; iodine; In xylene;

Reference yield:

7-hydroxy-7,8,9,10-tetrahydrobenzopyrene (6272-55-5,91484-77-4) → (+/-)-trans-7,8-Dihydrobenzopyrene-7,8-diol dibenzoate (57405-08-0,62654-79-9,63268-37-1,63268-38-2,64912-51-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 3.64 g / p-TsOH / benzene / 1 h / 50 °C

2: 60 percent / I₂

3: 57 percent / NBS

4: 50 percent / xylene

With N-Bromosuccinimide; iodine; toluene-4-sulfonic acid; In xylene; benzene;

upstream raw materials:

C₃₄H₂₃BrO₄

9,10-dihydro benzopyrene

7-hydroxy-7,8,9,10-tetrahydrobenzopyrene

silver benzoate

Downstream raw materials:

(-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene

(-)-7R-trans-Benzopyrene-7,8-dihydrodiol

(+/-)-trans-7,8-Dihydrobenzo[a]pyrene-7,8-diol

(+/-)-7β,8α,9α,10α-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene

Refernces