4-chloro-N'-[(dimethylamino)methylidene]benzohydrazide

Base Information

• Chemical Name: 4-chloro-N'-[(dimethylamino)methylidene]benzohydrazide
• CAS No.: 308239-37-4
• Molecular Formula: C₁₀H₁₂ClN₃O
• Molecular Weight: 225.678
• Hs Code.: 2929900090
• DSSTox Substance ID: DTXSID701191792
• Mol file: 308239-37-4.mol

Synonyms:4-chloro-N'-[(dimethylamino)methylidene]benzohydrazide;DTXSID701191792;HMS2658O22;AKOS030245250;4-Chlorobenzoic acid 2-[(dimethylamino)methylene]hydrazide

Chemical Property of 4-chloro-N'-[(dimethylamino)methylidene]benzohydrazide

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 225.0668897
• Heavy Atom Count: 15
• Complexity: 235

Purity/Quality:

N'-(4-CHLOROBENZOYL)-N,N-DIMETHYLHYDRAZONOFORMAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)C=NNC(=O)C1=CC=C(C=C1)Cl

Technology Process of 4-chloro-N'-[(dimethylamino)methylidene]benzohydrazide

There total 2 articles about 4-chloro-N'-[(dimethylamino)methylidene]benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

4-chlorobenzoic acid hydrazide (536-40-3) + N,N-Dimethyl-N'-(dimethylamino-methoxymethyl)-formamidin → N'-Dimethylaminomethylen-p-chlorbenzhydrazid (308239-37-4)

Guidance literature:

In tetrahydrofuran; for 0.5h; Heating;

Reference yield:

N,N-dimethyl-formamide dimethyl acetal (4637-24-5) + 4-chlorobenzoic acid hydrazide (536-40-3) → N'-Dimethylaminomethylen-p-chlorbenzhydrazid (308239-37-4)

Guidance literature:

In acetonitrile; at 60 ℃; for 1h;

DOI:10.1080/14756366.2019.1584622

upstream raw materials:

4-chlorobenzoic acid hydrazide

N,N-dimethyl-formamide dimethyl acetal