C₅₅H₈₆N₁₀O₁₃S

Base Information

• Chemical Name: C₅₅H₈₆N₁₀O₁₃S
• CAS No.: 1152267-01-0
• Molecular Formula: C₅₅H₈₆N₁₀O₁₃S
• Molecular Weight: 1127.41
• Mol file: 1152267-01-0.mol

Synonyms:

Chemical Property of C₅₅H₈₆N₁₀O₁₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₅H₈₆N₁₀O₁₃S

There total 1 articles about C₅₅H₈₆N₁₀O₁₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Fmoc L-Phe (35661-40-6) + Fmoc-Lys(tert-butoxycarbonyl) (71989-26-9) + (R)-Pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester (71989-31-6,109425-54-9,144829-96-9,101555-62-8) + Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine (187618-60-6) → C55H86N10O13S (1152267-01-0)

Guidance literature:

Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; With 2-chlorotrityl resin; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.5h; Automated synthesizer; Inert atmosphere;

With piperidine; In N,N-dimethyl-formamide; Automated synthesizer; Inert atmosphere;

N-Fmoc L-Phe; Fmoc-Lys(tert-butoxycarbonyl); (R)-Pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester; Further stages;

DOI:10.1016/j.bmc.2009.02.053

Reference yield:

C55H86N10O13S (1152267-01-0) → C55H84N10O12S (1152267-04-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane;

DOI:10.1016/j.bmc.2009.02.053

upstream raw materials:

N-Fmoc L-Phe

Fmoc-Lys(tert-butoxycarbonyl)

(R)-Pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester

Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine

Downstream raw materials:

C₅₅H₈₄N₁₀O₁₂S