PEG4-acid

Base Information

• Chemical Name: PEG4-acid
• CAS No.: 518044-49-0
• Molecular Formula: C₉H₁₈O₆
• Molecular Weight: 222.238
• Mol file: 518044-49-0.mol

Synonyms:

Chemical Property of PEG4-acid

Chemical Property:

• Boiling Point: 385.4±32.0 °C(Predicted)
• PKA: 4.28±0.10(Predicted)
• Density: 1.180±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hydroxy-PEG3-Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Hydroxy-Peg4-Acid is used in preparation of rapamycin analogs as mTOR inhibitors.

Technology Process of PEG4-acid

There total 1 articles about PEG4-acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester (186020-66-6,892154-71-1) → 3-{2-[2-(2-hydroxyethoxyl)ethoxy]ethoxy}propanoic acid (518044-49-0,117786-94-4)

Guidance literature:

With trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield:

3-{2-[2-(2-hydroxyethoxyl)ethoxy]ethoxy}propanoic acid (518044-49-0,117786-94-4) → C57H89N7O12

Guidance literature:

Multi-step reaction with 3 steps

1: caesium carbonate

2: sulfur trioxide pyridine complex

3: borane-pyridine complex; acetic acid / methanol / 20 °C

With borane-pyridine complex; sulfur trioxide pyridine complex; caesium carbonate; acetic acid; In methanol;

Reference yield:

3-{2-[2-(2-hydroxyethoxyl)ethoxy]ethoxy}propanoic acid (518044-49-0,117786-94-4) → benzyl 3-{2-[2-(2-oxoethoxyl)ethoxy]ethoxy}propanoate

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate

2: sulfur trioxide pyridine complex

With sulfur trioxide pyridine complex; caesium carbonate;

upstream raw materials:

3-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 518044-49-0 PEG4-acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send