C₄₂H₄₂Cl₂N₂P₂Pd

Base Information

• Chemical Name: C₄₂H₄₂Cl₂N₂P₂Pd
• CAS No.: 1453493-27-0
• Molecular Formula: C₄₂H₄₂Cl₂N₂P₂Pd
• Molecular Weight: 814.082
• Mol file: 1453493-27-0.mol

Synonyms:

Chemical Property of C₄₂H₄₂Cl₂N₂P₂Pd

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₄₂Cl₂N₂P₂Pd

There total 7 articles about C₄₂H₄₂Cl₂N₂P₂Pd which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.9%

dichloro(1,5-cyclooctadiene)palladium(II) (12107-56-1) + 6,6'-bis(diphenylphosphanyl)-N2,N2,N2',N2',4,4'-hexamethyl-1,1'-biphenyl-2,2'-diamine (1453493-24-7) → C42H42Cl2N2P2Pd (1453493-27-0)

Guidance literature:

In dichloromethane; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejic.201300473

Reference yield:

4-methyl-2-nitroaniline (89-62-3) → C42H42Cl2N2P2Pd (1453493-27-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: acetic acid; bromine / 2.5 h / 0 - 20 °C / Inert atmosphere; Schlenk technique; Heating

2.1: sulfuric acid; sodium nitrite / water / 1.25 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

2.2: 1 h / 70 °C / Inert atmosphere; Schlenk technique

3.1: copper / N,N-dimethyl-formamide / 100 °C / Inert atmosphere; Schlenk technique

4.1: zinc / methanol / Inert atmosphere; Schlenk technique; Reflux

4.2: Inert atmosphere; Schlenk technique

5.1: sodium hydride / tetrahydrofuran / 35 h / Inert atmosphere; Schlenk technique; Reflux

6.1: n-butyllithium / diethyl ether / 3 h / 0 °C / Inert atmosphere; Schlenk technique

6.2: 72 h / -40 °C / Inert atmosphere; Schlenk technique

7.1: dichloromethane / 12 h / Inert atmosphere; Schlenk technique

With n-butyllithium; sulfuric acid; bromine; copper; sodium hydride; acetic acid; zinc; sodium nitrite; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; 2.1: |Sandmeyer Reaction / 2.2: |Sandmeyer Reaction;

DOI:10.1002/ejic.201300473

Reference yield:

2,2'-dibromo-4,4'-dimethyl-6,6'-dinitro-1,1'-biphenyl (197961-57-2) → C42H42Cl2N2P2Pd (1453493-27-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: zinc / methanol / Inert atmosphere; Schlenk technique; Reflux

1.2: Inert atmosphere; Schlenk technique

2.1: sodium hydride / tetrahydrofuran / 35 h / Inert atmosphere; Schlenk technique; Reflux

3.1: n-butyllithium / diethyl ether / 3 h / 0 °C / Inert atmosphere; Schlenk technique

3.2: 72 h / -40 °C / Inert atmosphere; Schlenk technique

4.1: dichloromethane / 12 h / Inert atmosphere; Schlenk technique

With n-butyllithium; sodium hydride; zinc; In tetrahydrofuran; methanol; diethyl ether; dichloromethane;

DOI:10.1002/ejic.201300473

upstream raw materials:

dichloro(1,5-cyclooctadiene)palladium(II)

6,6'-bis(diphenylphosphanyl)-N₂,N₂,N₂',N₂',4,4'-hexamethyl-1,1'-biphenyl-2,2'-diamine

4-methyl-2-nitroaniline

2-bromo-4-methyl-6-nitroaniline