Technology Process of 6-benzyl-1,3,4-thiadiazin-5(6H)-one
There total 3 articles about 6-benzyl-1,3,4-thiadiazin-5(6H)-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydrogen sulfide monohydrate / water / 14 h / -5 °C / Heating
2: sulfuric acid / 6 h / Reflux
3: hydrazine hydrate / methanol / 24 h / -5 - 0 °C
4: acetic acid / 8 h / Inert atmosphere; Reflux
With
sodium hydrogen sulfide monohydrate; sulfuric acid; hydrazine hydrate; acetic acid;
In
methanol; water;
DOI:10.1016/j.tet.2012.02.071
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogen bromide; potassium bromide; sodium nitrite / water / 0 - 20 °C
2: sodium hydrogen sulfide monohydrate / water / 14 h / -5 °C / Heating
3: sulfuric acid / 6 h / Reflux
4: hydrazine hydrate / methanol / 24 h / -5 - 0 °C
5: acetic acid / 8 h / Inert atmosphere; Reflux
With
sodium hydrogen sulfide monohydrate; sulfuric acid; hydrogen bromide; hydrazine hydrate; acetic acid; potassium bromide; sodium nitrite;
In
methanol; water;
DOI:10.1016/j.tet.2012.02.071
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrazine hydrate / methanol / 24 h / -5 - 0 °C
2: acetic acid / 8 h / Inert atmosphere; Reflux
With
hydrazine hydrate; acetic acid;
In
methanol;
DOI:10.1016/j.tet.2012.02.071