2-Piperidinocinnamic acid

Base Information

• Chemical Name: 2-Piperidinocinnamic acid
• CAS No.: 83716-77-2
• Molecular Formula: C₁₄H₁₇NO₂
• Molecular Weight: 231.294
• Mol file: 83716-77-2.mol

Synonyms:

Chemical Property of 2-Piperidinocinnamic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Piperidinocinnamic acid

There total 1 articles about 2-Piperidinocinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

malonic acid (141-82-2) + 2-(piperidin-1-yl)benzaldehyde (34595-26-1) → 2-Piperidinocinnamic acid (83716-77-2)

Guidance literature:

With pyridine; for 5h; Heating;

DOI:10.1055/s-1982-29893

Reference yield:

2-Piperidinocinnamic acid (83716-77-2) → 2-Piperidinocinnamic acid amide (83716-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: 35 percent / NaHSO₃, NaHCO₃ / diethyl ether; H₂O / Ambient temperature

With sodium hydrogencarbonate; sodium hydrogensulfite; In diethyl ether; water;

DOI:10.1055/s-1982-29893

Reference yield:

isocyanate de chlorosulfonyle (1189-71-5) + 2-Piperidinocinnamic acid (83716-77-2) → C14H17ClN2O3S

Guidance literature:

In diethyl ether;

DOI:10.1055/s-1982-29893

upstream raw materials:

malonic acid

2-(piperidin-1-yl)benzaldehyde

Downstream raw materials:

2-Piperidinocinnamic acid amide