Technology Process of C17H13FN6O
There total 12 articles about C17H13FN6O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 12 steps
1: isopropyl alcohol / 50 °C
2: caesium carbonate / tetrahydrofuran; isopropyl alcohol
3: hydrogenchloride / water
4: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 75 °C
5: ammonium acetate; ammonium hydroxide; zinc / ethanol; water / 80 °C
6: N-ethyl-N,N-diisopropylamine / dichloromethane
7: trichlorophosphate / 100 °C
8: ammonia / methanol
9: trifluoroacetic anhydride / tetrahydrofuran; pyridine
10: hydrazine hydrate / methanol
11: N-ethyl-N,N-diisopropylamine / dichloromethane
12: ammonia / methanol / 100 °C
With
hydrogenchloride; hydroxylamine hydrochloride; ammonium acetate; ammonia; caesium carbonate; ammonium hydroxide; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; trifluoroacetic anhydride; sodium hydroxide; zinc; trichlorophosphate;
In
tetrahydrofuran; pyridine; methanol; ethanol; dichloromethane; water; isopropyl alcohol;
2: Horner-Emmons condensation;
DOI:10.1016/j.bmcl.2011.08.071
- Guidance literature:
-
Multi-step reaction with 10 steps
1: hydrogenchloride / water
2: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 75 °C
3: ammonium acetate; ammonium hydroxide; zinc / ethanol; water / 80 °C
4: N-ethyl-N,N-diisopropylamine / dichloromethane
5: trichlorophosphate / 100 °C
6: ammonia / methanol
7: trifluoroacetic anhydride / tetrahydrofuran; pyridine
8: hydrazine hydrate / methanol
9: N-ethyl-N,N-diisopropylamine / dichloromethane
10: ammonia / methanol / 100 °C
With
hydrogenchloride; hydroxylamine hydrochloride; ammonium acetate; ammonia; ammonium hydroxide; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; trifluoroacetic anhydride; sodium hydroxide; zinc; trichlorophosphate;
In
tetrahydrofuran; pyridine; methanol; ethanol; dichloromethane; water;
DOI:10.1016/j.bmcl.2011.08.071