dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

Base Information

Chemical Name:dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate
CAS No.:1448300-64-8
Molecular Formula:C₁₃H₁₄ClNO₆
Molecular Weight:315.71
Hs Code.:

Synonyms:

Suppliers and Price of dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

There total 2 articles about dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 37888-03-2,3156-35-2
3-chloroβ-nitrostyrene

: 108-59-8
malonic acid dimethyl ester

: 1448300-63-7
(S)-dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

: 1448300-64-8
dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

Guidance literature:: With C₄₆H₅₇N₃O₈; triethylamine; In toluene; at -78 ℃; for 72h; Overall yield = 96 %; Overall yield = 61 mg; enantioselective reaction;
DOI:10.1021/acs.orglett.9b01170

Reference yield:

: 75-52-5
nitromethane

: 587-04-2
m-Chlorobenzaldehyde

: 108-59-8
malonic acid dimethyl ester

: 1448300-63-7
(S)-dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

: 1448300-64-8
dimethyl 2-(2-nitro-1-(3-chlorophenyl)-ethyl)malonate

Guidance literature:: With cinchona alkaloid and aminopropyl group-based hybrid organic-inorganic catalyst; In 1,4-dioxane; at 70 ℃; for 36h; Overall yield = 71 %; enantioselective reaction;
DOI:10.1039/c3sc22310h