2,5-Dimethoxy-3,6-dimethylbenzaldehyde

Base Information

• Chemical Name: 2,5-Dimethoxy-3,6-dimethylbenzaldehyde
• CAS No.: 104129-40-0
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• DSSTox Substance ID: DTXSID70544880
• Wikidata: Q82422175
• Mol file: 104129-40-0.mol

Synonyms:2,5-dimethoxy-3,6-dimethylbenzaldehyde;104129-40-0;SCHEMBL6314730;DTXSID70544880;MAHSGSRMRDCYSY-UHFFFAOYSA-N;2,5-dimethoxy-3,6-dimethyl-benzaldehyde

Chemical Property of 2,5-Dimethoxy-3,6-dimethylbenzaldehyde

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 193

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1OC)C=O)C)OC

Technology Process of 2,5-Dimethoxy-3,6-dimethylbenzaldehyde

There total 3 articles about 2,5-Dimethoxy-3,6-dimethylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethyl-4-methoxyphenol (4962-28-1) → 2,5-dimethoxy-3,6-dimethylbenzaldehyde (104129-40-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / triethylamine; MgCl₂ / acetonitrile / 8 h / Heating

2: 96 percent / K₂CO₃ / dimethylformamide

With potassium carbonate; triethylamine; magnesium chloride; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo060790g

Reference yield:

1,4-dimethoxy-2,5-dimethylbenzene (2674-32-0) → 2,5-dimethoxy-3,6-dimethylbenzaldehyde (104129-40-0)

Guidance literature:

With hydrogenchloride; aluminium trichloride; benzene; Erhitzen des Reaktionsprodukts mit wss. HCl;

DOI:10.1021/jo01203a008 DOI:10.1021/ja01283a021

Reference yield:

2,5-dimethylhydroquinone (615-90-7) → 2,5-dimethoxy-3,6-dimethylbenzaldehyde (104129-40-0)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol. KOH

2: HCl; AlCl₃; benzene / Erhitzen des Reaktionsprodukts mit wss. HCl

With hydrogenchloride; potassium hydroxide; aluminium trichloride; benzene;

DOI:10.1021/jo01203a008 DOI:10.1021/ja01283a021

upstream raw materials:

1,4-dimethoxy-2,5-dimethylbenzene

2,5-dimethyl-4-methoxyphenol

2,5-dimethylhydroquinone

Downstream raw materials:

(2,5-dimethoxy-3,6-dimethyl-benzylidene)-malonic acid

1-(2,5-dimethoxy-3,6-dimethyl-phenyl)-ethanol

2,5-dimethoxy-3,6-dimethylphenol

(E)-3-[4-(n-heptyloxy)-2,5-dimethoxy-3,6-dimethylphenyl]-2-[5-(3-pyridyl)pentyl]-2-propenoic acid