4962-28-1

Basic information

• Product Name: Phenol, 4-methoxy-2,5-dimethyl-
• Synonyms: 4-Methoxy-2,5-dimethyl-phenol;Methyl-(4-hydroxy-2.5-dimethyl-phenyl)-aether;5-Hydroxy-2-methoxy-p-xylol;4-methoxy-2,5-xylenol;4-methoxy-2,5-dimethylphenol;2,5-Dimethyl-4-methoxy-phenol
• CAS NO: 4962-28-1
• Molecular Formula: C9H12O2
• Molecular Weight: 152.193
• Mol File: 4962-28-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 90 °C
• Boiling Point: 259.9±35.0 °C(Predicted)
• Density: 1.053±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Phenol, 4-methoxy-2,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-methoxy-2,5-dimethyl-(4962-28-1)
• EPA Substance Registry System: Phenol, 4-methoxy-2,5-dimethyl-(4962-28-1)

Safety Data

• Hazardous Substances Data: 4962-28-1(Hazardous Substances Data)

Upstream product

• 6745-75-1 2,5-dimethyl-p-anisaldehyde 
• 117174-70-6 4-methoxy-2,5-dimethylaniline 
• 3139-06-8 1-methoxy-2,5-dimethyl-4-nitrobenzene 
• 615-90-7 2,5-dimethylhydroquinone 
• 77-78-1 dimethyl sulfate 
• 58106-25-5 1-bromo-4-methoxy-2,5-dimethylbenzene 
• 3096-64-8 N-(2,5-dimethylphenyl)hydroxylamine 
• 137-18-8 2,5-Dimethyl-1,4-benzoquinone 
• 67-66-3 chloroform 
• 10028-15-6 ozone 
• 121-45-9 phosphorous acid trimethyl ester 
• 7509-05-9 phosphoric acid-(4-methoxy-2,5-dimethyl-phenyl ester)-dimethyl ester 
• 67-56-1 methanol 
• 1198-37-4 2,4-dimethylquinoline 

Downstream Products

• 104129-40-0 2,5-dimethoxy-3,6-dimethylbenzaldehyde 
• 91244-98-3 1-chloromethyl-2,5-dimethoxy-3,6-dimethylbenzene 
• 906477-66-5 2,5-dimethyl-3-[(4-trifluoromethylphenoxy)methyl]-6-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 906477-65-4 2,5-dimethyl-3-[(4-cyanophenoxy)methyl]-6-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 863705-28-6 2-[(4-cyanobenzoyloxy)methyl]-3,6-dimethyl-5-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 863705-21-9 2-[(phenylacetyloxy)methyl]-3,6-dimethyl-5-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 863705-20-8 2-[(benzoyloxy)methyl]-3,6-dimethyl-5-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 863705-15-1 2,5-dimethyl-3-(phenoxymethyl)-6-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 863705-25-3 2-(hydroxymethyl)-3,6-dimethyl-5-pyrrolidino-2,5-cyclohexadiene-1,4-dione 
• 863705-26-4 1-(phenoxymethyl)-2,5-dimethoxy-3,6-dimethylbenzene 
• 863705-27-5 2,5-dimethyl-3-(phenoxymethyl)-2,5-cyclohexadiene-1,4-dione 
• 863705-23-1 2-hydroxy-5-methoxy-3,6-dimethylbenzenemethanol 
• 327615-03-2 2,5-dimethoxy-3,6-dimethylbenzenemethanol 
• 863705-24-2 2-(hydroxymethyl)-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione 

Relevant articles and documents

AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS

In one aspect, the present disclosure provides methods of preparing a primary or secondary amine and hydroxylated aromatic compounds. In some embodiments, the aromatic compound may be unsubstituted, substituted, or contain one or more heteroatoms within the rings of the aromatic compound. The methods described herein may be carried out without the need for transition metal catalysts or harsh reaction conditions.

Palladium-catalyzed hydroxylation of aryl and heteroaryl halides enabled by the use of a palladacycle precatalyst

A method for the hydroxylation of aryl and heteroaryl halides, promoted by a catalyst based on a biarylphosphine ligand tBuBrettPhos (L5) and its corresponding palladium precatalyst (1), is described. The reactions allow the cross-coupling of both potassium and cesium hydroxides with (hetero)aryl halides to afford a variety of phenols and hydroxylated heteroarenes in high to excellent yield.