Technology Process of N1-(2-iodophenyl)-N1,N4-dimethyl-N4-(o-tolylsulfonyl)fumaramide
There total 5 articles about N1-(2-iodophenyl)-N1,N4-dimethyl-N4-(o-tolylsulfonyl)fumaramide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
DOI:10.1039/c2cc15670a
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C
1.2: 0 - 20 °C
2.1: ethanol; potassium hydroxide / 20 °C
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0.5 h / 0 - 20 °C
4.1: triethylamine / dichloromethane / 0 - 20 °C
With
oxalyl dichloride; ethanol; sodium hydride; triethylamine; N,N-dimethyl-formamide; potassium hydroxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1039/c2cc15670a
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 4-methyl-morpholine; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride / tetrahydrofuran / 0.33 h / 20 °C
2.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C
2.2: 0 - 20 °C
3.1: ethanol; potassium hydroxide / 20 °C
4.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0.5 h / 0 - 20 °C
5.1: triethylamine / dichloromethane / 0 - 20 °C
With
4-methyl-morpholine; oxalyl dichloride; ethanol; sodium hydride; triethylamine; N,N-dimethyl-formamide; 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; potassium hydroxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1039/c2cc15670a
