2-oxo-3-quinolin-4-yl-propionic acid ethyl ester

Base Information

• Chemical Name: 2-oxo-3-quinolin-4-yl-propionic acid ethyl ester
• CAS No.: 13119-77-2
• Molecular Formula: C₁₄H₁₃NO₃
• Molecular Weight: 243.262
• Mol file: 13119-77-2.mol

Synonyms:

Chemical Property of 2-oxo-3-quinolin-4-yl-propionic acid ethyl ester

Chemical Property:

Purity/Quality:

95+% ^*data from raw suppliers

Ethyl2-oxo-3-(quinolin-4-yl)propanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-oxo-3-quinolin-4-yl-propionic acid ethyl ester

There total 1 articles about 2-oxo-3-quinolin-4-yl-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C6H4NCH2CHCCH2 (491-35-0) + oxalic acid diethyl ester (95-92-1) → 2-oxo-3-quinolin-4-yl-propionic acid ethyl ester (13119-77-2)

Guidance literature:

With diethyl ether; ethanol; potassium ethoxide;

Reference yield:

2-oxo-3-quinolin-4-yl-propionic acid ethyl ester (13119-77-2) → 2-(quinolin-4-yl)acetonitrile (14003-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

2: acetic acid anhydride / Erhitzen auf Siedetemperatur

With sodium hydroxide; acetic anhydride;

Reference yield:

2-oxo-3-quinolin-4-yl-propionic acid ethyl ester (13119-77-2) → DL-β-Chinol-4-ylalanin (1991-98-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

2: SnCl₂; concentrated aqueous HCl

With hydrogenchloride; sodium hydroxide; tin(ll) chloride;

upstream raw materials:

C₆H₄NCH₂CHCCH₂

oxalic acid diethyl ester

Downstream raw materials:

DL-β-Chinol-4-ylalanin

2-(quinolin-4-yl)acetonitrile

[4]quinolyl-(4-dimethylamino-phenylimino)-acetonitrile