C₃₀H₂₃FN₄O₃

Base Information

Chemical Name:C₃₀H₂₃FN₄O₃
CAS No.:1430200-08-0
Molecular Formula:C₃₀H₂₃FN₄O₃
Molecular Weight:506.536
Hs Code.:

C<sub>30</sub>H<sub>23</sub>FN<sub>4</sub>O<sub>3</sub>

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₃₀H₂₃FN₄O₃

Chemical Property:

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Technology Process of C₃₀H₂₃FN₄O₃

There total 7 articles about C₃₀H₂₃FN₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1430200-27-3
(5R)-5-benzyl-5-(5-bromo-1H-benzimidazol-2-yl)-3-[(1R)-1-(4-fluorophenyl)ethyl]-1,3-oxazolidine-2,4-dione

: 1692-25-7
3-pyridylboronic acid

: 1430200-08-0
C₃₀H₂₃FN₄O₃

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; In ethanol; at 120 ℃; for 0.0833333h; Microwave irradiation;
DOI:10.1021/acsmedchemlett.5b00010

Reference yield:

: C₁₈H₁₇BrN₂O₃

: 1430200-08-0
C₃₀H₂₃FN₄O₃

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / 0.42 h / 70 °C

2: palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate / ethanol / 0.08 h / 120 °C / Microwave irradiation

With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; sodium hydroxide; In ethanol; 2: |Suzuki Coupling;
DOI:10.1021/acsmedchemlett.5b00010

Reference yield:

: 56150-08-4
diethyl α-benzyl α-hydroxymalonate

: 1430200-08-0
C₃₀H₂₃FN₄O₃

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium hydroxide / ethanol / 20 °C

1.2: pH 2

2.1: chiral SFC (OJ-H, 4.6 x 100 mm) / methanol; trifluoroacetic acid / 75007.5 Torr / Resolution of racemate

3.1: N,N-dimethyl-formamide; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / 20 °C

3.2: 2 h / 75 °C

4.1: sodium hydroxide / 0.42 h / 70 °C

5.1: palladium diacetate; 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate / ethanol / 0.08 h / 120 °C / Microwave irradiation

With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; potassium hydroxide; sodium hydroxide; In methanol; ethanol; trifluoroacetic acid; 5.1: |Suzuki Coupling;
DOI:10.1021/acsmedchemlett.5b00010