2,3-DIMETHYLBENZOIC ACID ETHYL ESTER

Base Information

• Chemical Name: 2,3-DIMETHYLBENZOIC ACID ETHYL ESTER
• CAS No.: 104175-24-8
• Molecular Formula: C11H14O2
• Molecular Weight: 178.22800
• Hs Code.: 2916399090
• Mol file: 104175-24-8.mol

Synonyms:2,3-DiMethylbenzoic Acid Ethyl Ester;

Chemical Property of 2,3-DIMETHYLBENZOIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 0.0192mmHg at 25°C
• Boiling Point: 252.5oC at 760 mmHg
• Flash Point: 111.1oC
• PSA: 26.30000
• Density: 1.01g/cm3
• LogP: 2.48010

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2,3-Dimethylbenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-DIMETHYLBENZOIC ACID ETHYL ESTER

There total 3 articles about 2,3-DIMETHYLBENZOIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

benzaldehyde dimethyl acetal (1125-88-8) + 3-bromo-2-methyl-benzoic acid ethyl ester (103038-43-3) → ethyl 2,3-dimethylbenzoate (104175-24-8)

Guidance literature:

With nickel(II) bromide dimethoxyethane; potassium phosphate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; 4,4'-di-tert-butyl-2,2'-bipyridine; In acetonitrile; benzene; for 24h; Glovebox; Sealed tube; Irradiation;

DOI:10.1021/jacs.1c12203

Reference yield:

ethanol (64-17-5) + 2,3-dimethylbenzoic acid (603-79-2) → ethyl 2,3-dimethylbenzoate (104175-24-8)

Guidance literature:

With sulfuric acid; Reflux;

DOI:10.1007/s11010-016-2888-6

Reference yield:

→ ethyl 2,3-dimethylbenzoate (104175-24-8)

Guidance literature:

3,4-Dimethyl-4-ethoxycarbonyl-cyclohexadien-(2,5)-ol-(1), Umlagerung (10percentig. H2SO4);

upstream raw materials:

ethanol

2,3-dimethylbenzoic acid

benzaldehyde dimethyl acetal

3-bromo-2-methyl-benzoic acid ethyl ester

Downstream raw materials:

2,3-dimethyl-benzoic acid hydrazide