Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate

Base Information

• Chemical Name: Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate
• CAS No.: 16323-00-5
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.272
• Mol file: 16323-00-5.mol

Synonyms:

Chemical Property of Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate

Chemical Property:

• Boiling Point: 350.2±27.0 °C(Predicted)
• PKA: 10.07±0.15(Predicted)
• Density: 1.151±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

99% ^*data from raw suppliers

Ethyl2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate

There total 2 articles about Ethyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + 2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid (658-48-0,5380-13-2) → α-methyltyrosine ethyl ester (16323-00-5)

Guidance literature:

ethanol; 2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid; With thionyl chloride; at 20 ℃; for 4h;

With triethylamine;

Reference yield:

→ α-methyltyrosine ethyl ester (16323-00-5)

Guidance literature:

Aminosaeure III, EtOH, HCl, reflux;

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + α-methyltyrosine ethyl ester (16323-00-5) → HO-Pr-AMT

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide;

upstream raw materials:

ethanol

2-amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid

Refernces