3-Amino-2,6-dimethylquinazolin-4(3H)-one

Base Information

Chemical Name:3-Amino-2,6-dimethylquinazolin-4(3H)-one
CAS No.:85516-81-0
Molecular Formula:C₁₀H₁₁N₃O
Molecular Weight:189.217
Hs Code.:
European Community (EC) Number:668-189-8

Synonyms:3-Amino-2,6-dimethylquinazolin-4(3H)-one;85516-81-0;AKOS022643074;3-amino-2,6-dimethyl-3,4-dihydroquinazolin-4-one;3-AMINO-2,6-DIMETHYL-4(3H)-QUINAZOLINONE

Suppliers and Price of 3-Amino-2,6-dimethylquinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Amino-2,6-dimethylquinazolin-4(3H)-one

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:189.090211983
Heavy Atom Count:14
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)N=C(N(C2=O)N)C

Technology Process of 3-Amino-2,6-dimethylquinazolin-4(3H)-one

There total 2 articles about 3-Amino-2,6-dimethylquinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 28461-49-6
2-Amino-5-methylbenzoic Acid Hydrazide

: 78-39-7
Triethyl orthoacetate

: 96134-67-7
4-Methyl-2-(5-methyl-1,3,4-oxadiazol-2-yl)benzeneamine

: 85516-74-1
dimethyl-2,7 dihydro-3,4 benzotriazepine-1,3,4 (5H) one-5

: 85516-81-0
amino-3 dimethyl-2,6 (3H) quinazolinone-4

Guidance literature:: In ethanol; for 16h; Product distribution; Heating; molar ratio 2-aminobenzoic acid hydrazide and triethyl orthoformate 1:1, other molar ratio;

Reference yield:

: 85516-74-1
dimethyl-2,7 dihydro-3,4 benzotriazepine-1,3,4 (5H) one-5

: 96134-67-7
4-Methyl-2-(5-methyl-1,3,4-oxadiazol-2-yl)benzeneamine

: 85516-81-0
amino-3 dimethyl-2,6 (3H) quinazolinone-4

Guidance literature:: With toluene-4-sulfonic acid; In toluene; for 1.5h; Product distribution; Heating;

Reference yield:

: 85516-81-0
amino-3 dimethyl-2,6 (3H) quinazolinone-4

: 1382052-27-8
6-amino-1-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: Reflux

2: piperidine / 1,4-dioxane / 3 h / Reflux

3: triethylamine / 1,4-dioxane / 6 h / Reflux

With piperidine; triethylamine; In 1,4-dioxane;
DOI:10.1016/j.ejmech.2012.03.044