Technology Process of {[2-(Bromomethyl)phenyl]methyl}(trimethyl)silane
There total 4 articles about {[2-(Bromomethyl)phenyl]methyl}(trimethyl)silane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; triphenylphosphine;
In
diethyl ether;
at 25 ℃;
for 0.5h;
DOI:10.1021/ja00243a029
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) n-BuLi / 1) Et2O, hexane, 0 deg C to room temperature; reflux, 24 h, 2) Et2O, hexane, -78 deg C to room temperature; room temperature, 2 h
2: 112.6 g / 10percent H2SO4 / diethyl ether; hexane
3: 95 percent / PBr3 / diethyl ether / 2 h / Ambient temperature
With
n-butyllithium; sulfuric acid; phosphorus tribromide;
In
diethyl ether; hexane;
DOI:10.1021/jo970592c
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 112.6 g / 10percent H2SO4 / diethyl ether; hexane
2: 95 percent / PBr3 / diethyl ether / 2 h / Ambient temperature
With
sulfuric acid; phosphorus tribromide;
In
diethyl ether; hexane;
DOI:10.1021/jo970592c
![2-[(trimethylsilyl)methyl]benzyl alcohol](/Databaselist/images/loading.webp)
