o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether

Base Information

• Chemical Name: o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether
• CAS No.: 83781-92-4
• Molecular Formula: C₁₄H₂₆OSi₂
• Molecular Weight: 266.531
• Mol file: 83781-92-4.mol

Synonyms:o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether

Chemical Property of o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether

There total 1 articles about o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + 2-methyl-benzyl alcohol (89-95-2) → o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether (83781-92-4)

Guidance literature:

With n-butyllithium;

Reference yield: 87.0%

o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether (83781-92-4) → 2-[(trimethylsilyl)methyl]benzyl alcohol (57754-01-5)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; water; for 2h;

DOI:10.1021/ja00243a029

Reference yield:

o-[(trimethylsilyl)methyl]benzyl trimethylsilyl ether (83781-92-4) → 2-(trimethylsilylmethyl)benzyl bromide (104330-78-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 112.6 g / 10percent H₂SO₄ / diethyl ether; hexane

2: 95 percent / PBr₃ / diethyl ether / 2 h / Ambient temperature

With sulfuric acid; phosphorus tribromide; In diethyl ether; hexane;

DOI:10.1021/jo970592c

upstream raw materials:

chloro-trimethyl-silane

2-methyl-benzyl alcohol

Downstream raw materials:

2-[(trimethylsilyl)methyl]benzyl alcohol

(E)-1-methyl-2-(penta-2,4-dien-2-yl)benzene

(E)-1-(but-2-en-2-yl)-2-methylbenzene

1-Methyl-2-(1-methylene-but-3-enyl)-benzene