2-cyclooctylethanol

Base Information

• Chemical Name: 2-cyclooctylethanol
• CAS No.: 4744-93-8
• Molecular Formula: C₁₀H₂₀O
• Molecular Weight: 156.268
• Mol file: 4744-93-8.mol

Synonyms:

Chemical Property of 2-cyclooctylethanol

Chemical Property:

• Vapor Pressure: 0.00789mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-cyclooctylethanol

There total 17 articles about 2-cyclooctylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

ethyl 2-cyclooctylacetate (80246-71-5) → 2-cyclooctylethan-1-ol (4744-93-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1248/cpb.40.2391

Reference yield: 53.6%

cyclooctylacetic acid methyl ester (161785-96-2) → 2-cyclooctylethan-1-ol (4744-93-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 50 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c9cc01330j

Reference yield:

cycloactanone (502-49-8) → 2-cyclooctylethan-1-ol (4744-93-8)

Guidance literature:

Multi-step reaction with 4 steps

1: zinc; benzene / Behandeln des Reaktionsprodukts mit Phosphor(III)-bromid in Benzol und Erhitzen des danach isolierten Esters mit aethanol. Kalilauge

2: acetic acid; platinum / Hydrogenation

3: ethanolic sulfuric acid

4: sodium; ethanol

With ethanol; sulfuric acid; sodium; acetic acid; platinum; zinc; benzene;

DOI:10.1002/hlca.19310140615

upstream raw materials:

2-cyclooctatetraenyl-ethanol

ethyl 2-cyclooctylacetate

ethyl cycloocten-1-ylacetate

2-(cyclooct-1-enyl)ethanol

Downstream raw materials:

7-Chloro-2-[2-(4-methyl-cyclohexyl)-ethyl]-6-nitro-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

7-Hydroxy-2-[2-(4-methyl-cyclohexyl)-ethyl]-6-nitro-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

7-Amino-2-[2-(4-methyl-cyclohexyl)-ethyl]-6-nitro-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one

7-Hydroxy-2-[2-(4-methyl-cyclohexyl)-ethyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one