parf-1,1-Dicyano-2-methyl-3-phenylbutane

Base Information

• Chemical Name: parf-1,1-Dicyano-2-methyl-3-phenylbutane
• CAS No.: 88106-72-3
• Molecular Formula: C₁₃H₁₄N₂
• Molecular Weight: 198.268
• Mol file: 88106-72-3.mol

Synonyms:

Chemical Property of parf-1,1-Dicyano-2-methyl-3-phenylbutane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of parf-1,1-Dicyano-2-methyl-3-phenylbutane

There total 13 articles about parf-1,1-Dicyano-2-methyl-3-phenylbutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-(2-phenylpropylidene)propanedinitrile (88106-71-2) + methyl iodide (74-88-4) → pref-1,1-Dicyano-2-methyl-3-phenylbutane (88106-73-4) + parf-1,1-Dicyano-2-methyl-3-phenylbutane (88106-72-3)

Guidance literature:

With magnesium; In diethyl ether; for 0.5h; Product distribution; Mechanism; Ambient temperature; other temperature, inverse addition; further reaction with other alkyl(aryl) Grignards, alkyllithiums and lithium dialkyl(diaryl)cuprates;

DOI:10.1021/jo00179a008

Reference yield:

2-(2-phenylpropylidene)propanedinitrile (88106-71-2) → pref-1,1-Dicyano-2-methyl-3-phenylbutane (88106-73-4) + parf-1,1-Dicyano-2-methyl-3-phenylbutane (88106-72-3)

Guidance literature:

at -78 - -20 ℃; for 1.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/ja00210a061

Reference yield:

2-(2-phenylpropylidene)propanedinitrile (88106-71-2) → pref-1,1-Dicyano-2-methyl-3-phenylbutane (88106-73-4) + parf-1,1-Dicyano-2-methyl-3-phenylbutane (88106-72-3)

Guidance literature:

at -78 - 0 ℃; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/ja00210a061

upstream raw materials:

2-(2-phenylpropylidene)propanedinitrile

methylcopper

methyl iodide

3-phenyl-butan-2-one

Downstream raw materials:

parf-1,1-Dicarbomethoxy-2-methyl-3-phenylbutane

Refernces

• 1、 Yamamoto, Yoshinori,Nishii, Shinji,Ibuka, Toshiro. "Acyclic Stereocontrol via an Electron-Transfer Process. Remarkable Stereochemical Difference between One- and Two-Electron Events". . p. 617 - 618. Retrieved 2007/10/02.