C₂₅H₂₇N₅O₄

Base Information

• Chemical Name: C₂₅H₂₇N₅O₄
• CAS No.: 1383439-86-8
• Molecular Formula: C₂₅H₂₇N₅O₄
• Molecular Weight: 461.52
• Mol file: 1383439-86-8.mol

Synonyms:

Chemical Property of C₂₅H₂₇N₅O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₇N₅O₄

There total 10 articles about C₂₅H₂₇N₅O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Hydroxy-2-pentanone (1071-73-4) → C25H27N5O4 (1383439-86-8)

Guidance literature:

Multi-step reaction with 7 steps

1: pyridine / dichloromethane / 24 h

2: bromine / diethyl ether / 95 h / 5 °C

3: sodium azide / water; acetone / 20 °C

4: triphenylphosphine / 1,4-dioxane / 3 h / 75 °C

5: sodium hydroxide / ethanol / 2 h / 20 °C

6: triethylamine / dichloromethane / 1 h / 0 °C

7: potassium carbonate / acetonitrile / 24 h / Reflux

With pyridine; sodium azide; bromine; potassium carbonate; triethylamine; triphenylphosphine; sodium hydroxide; In 1,4-dioxane; diethyl ether; ethanol; dichloromethane; water; acetone; acetonitrile;

DOI:10.1246/cl.2012.406

Reference yield:

3-bromo-4-carbonylpentyl benzoate (1352085-98-3) → C25H27N5O4 (1383439-86-8)

Guidance literature:

Multi-step reaction with 5 steps

1: sodium azide / water; acetone / 20 °C

2: triphenylphosphine / 1,4-dioxane / 3 h / 75 °C

3: sodium hydroxide / ethanol / 2 h / 20 °C

4: triethylamine / dichloromethane / 1 h / 0 °C

5: potassium carbonate / acetonitrile / 24 h / Reflux

With sodium azide; potassium carbonate; triethylamine; triphenylphosphine; sodium hydroxide; In 1,4-dioxane; ethanol; dichloromethane; water; acetone; acetonitrile;

DOI:10.1246/cl.2012.406

Reference yield:

3-azido-4-carbonylpentyl benzoate (1352085-99-4) → C25H27N5O4 (1383439-86-8)

Guidance literature:

Multi-step reaction with 4 steps

1: triphenylphosphine / 1,4-dioxane / 3 h / 75 °C

2: sodium hydroxide / ethanol / 2 h / 20 °C

3: triethylamine / dichloromethane / 1 h / 0 °C

4: potassium carbonate / acetonitrile / 24 h / Reflux

With potassium carbonate; triethylamine; triphenylphosphine; sodium hydroxide; In 1,4-dioxane; ethanol; dichloromethane; acetonitrile;

DOI:10.1246/cl.2012.406

upstream raw materials:

C₁₂H₁₆O₃

C₁₄H₁₅N₅O₄S

3-bromo-4-carbonylpentyl benzoate

3-azido-4-carbonylpentyl benzoate

Downstream raw materials:

3-[2-ethyl-4-(2-{5-methyl-2-[4-(1H-tetrazol-5-yl)phenyl]oxazol-4-yl}ethoxy)phenyl]propanoic acid