C₁₅H₁₇ClO

Base Information

• Chemical Name: C₁₅H₁₇ClO
• CAS No.: 1432499-31-4
• Molecular Formula: C₁₅H₁₇ClO
• Molecular Weight: 248.752
• Mol file: 1432499-31-4.mol

Synonyms:

Chemical Property of C₁₅H₁₇ClO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₇ClO

There total 5 articles about C₁₅H₁₇ClO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H25ClOSi (1432499-30-3) → C15H17ClO (1432499-31-4)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at -78 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/ja4025963

Reference yield:

2-phenylhex-5-enoic acid (156297-00-6) → C15H17ClO (1432499-31-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / 0 - 20 °C / Inert atmosphere

2.1: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C / Inert atmosphere

3.1: zinc; ammonium chloride / toluene; water; tetrahydrofuran / 10 h / 0 - 20 °C / Inert atmosphere

4.1: zinc dibromide; lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 - -20 °C / Inert atmosphere

4.2: 2 h / -78 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere

With lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; ammonium chloride; pyridinium chlorochromate; zinc dibromide; zinc; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; water; toluene;

DOI:10.1021/ja4025963

Reference yield:

2-phenyl-5-hexen-1-ol (177037-77-3) → C15H17ClO (1432499-31-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C / Inert atmosphere

2.1: zinc; ammonium chloride / toluene; water; tetrahydrofuran / 10 h / 0 - 20 °C / Inert atmosphere

3.1: zinc dibromide; lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 - -20 °C / Inert atmosphere

3.2: 2 h / -78 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; ammonium chloride; pyridinium chlorochromate; zinc dibromide; zinc; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; water; toluene;

DOI:10.1021/ja4025963

upstream raw materials:

2-phenylhex-5-enoic acid

2-phenyl-5-hexen-1-ol

2-phenyl-5-hexenal

C₁₅H₁₈O

Downstream raw materials:

C₁₅H₁₅ClO