1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl

Base Information

• Chemical Name: 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl
• CAS No.: 73282-13-0
• Molecular Formula: C₂₈H₂₀N₂O₄S₂
• Molecular Weight: 512.61
• Mol file: 73282-13-0.mol

Synonyms:

Chemical Property of 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl

There total 17 articles about 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-Bromo-4-picoline (4926-28-7) + (1-(benzenesulfonyl)-2-indolyl)zinc chloride → 1-(benzenesulfonyl)-2-(4-methyl-2-pyridyl)indole (152191-21-4) + 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl (73282-13-0)

Guidance literature:

bis-triphenylphosphine-palladium(II) chloride; diisobutylaluminium hydride; In tetrahydrofuran; for 4h; Heating; other substrates, other reactant;

DOI:10.1016/S0040-4039(00)74069-X

Reference yield: 46.0%

2-(trimethylstannyl)-N-(benzenesulfonyl)indole → 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl (73282-13-0)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; 2-chloro-6-(MOM-O-)pyridine; at 100 ℃; for 24h;

DOI:10.1016/j.tet.2008.09.101

Reference yield: 39.0%

1-benzenesulfonyl-2-tri-n-butylstannyl-1H-indole → 1,1'-bis-benzenesulfonyl-1H,1'H-[2,2']biindolyl (73282-13-0)

Guidance literature:

With copper(II) nitrate; In tetrahydrofuran; Ambient temperature;

DOI:10.1016/0040-4039(94)02231-Y

upstream raw materials:

2-chloropyridine

2-bromo-pyridine

2-chloro-4-picoline

2-Bromo-4-picoline

Refernces

• 1、 Bourderioux, Aurélie,Kassis, Paméla,Mérour, Jean-Yves,Routier, Sylvain. "Synthesis of new fused and substituted benzo and pyrido carbazoles via C-2 (het)arylindoles". scheme or table. p. 11012 - 11019. Retrieved 2009/04/11.
• 2、 Amat, Mercedes,Hadida, Sabine,Bosch, Joan. "An Efficient Synthesis of 2-(2-Pyridyl)indoles by Palladium(0)-catalyzed Heteroarylation". . p. 5005 - 5006. Retrieved 2007/10/02.