Technology Process of C30H30FN3O4S
There total 5 articles about C30H30FN3O4S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: tetrahydrofuran / 0.5 h / 0 °C
2.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C
3.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C
3.2: 1.5 h / 35 °C
4.1: hydrogenchloride; water / 1 h / 120 °C
5.1: triethylamine / tetrahydrofuran; water / 18 h / 20 °C
6.1: Chiralpak AD-H / liquid carbon dioxide; ethanol / Resolution of racemate
With
hydrogenchloride; potassium tert-butylate; water; caesium carbonate; triethylamine;
In
tetrahydrofuran; ethanol; liquid carbon dioxide; water; N,N-dimethyl-formamide;
1.1: Peterson olefination / 2.1: Peterson olefination;
DOI:10.1016/j.bmcl.2011.12.073
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / 0 °C
2.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C
2.2: 1.5 h / 35 °C
3.1: hydrogenchloride; water / 1 h / 120 °C
4.1: triethylamine / tetrahydrofuran; water / 18 h / 20 °C
5.1: Chiralpak AD-H / liquid carbon dioxide; ethanol / Resolution of racemate
With
hydrogenchloride; potassium tert-butylate; water; caesium carbonate; triethylamine;
In
tetrahydrofuran; ethanol; liquid carbon dioxide; water; N,N-dimethyl-formamide;
1.1: Peterson olefination;
DOI:10.1016/j.bmcl.2011.12.073
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride; water / 1 h / 120 °C
2: triethylamine / tetrahydrofuran; water / 18 h / 20 °C
3: Chiralpak AD-H / liquid carbon dioxide; ethanol / Resolution of racemate
With
hydrogenchloride; water; triethylamine;
In
tetrahydrofuran; ethanol; liquid carbon dioxide; water;
DOI:10.1016/j.bmcl.2011.12.073