Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester

Base Information

• Chemical Name: Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester
• CAS No.: 74426-44-1
• Molecular Formula: C₅₂H₅₁Cl₄N₃O₁₇
• Molecular Weight: 1131.8
• Mol file: 74426-44-1.mol

Synonyms:

Chemical Property of Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester

There total 19 articles about Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-galactopyranoside (76573-31-4) + 3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-α-D-glucopyranosyl bromide (3068-36-8) → Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8)

Guidance literature:

With tribenzylamine; silver perchlorate; In benzene; at 20 - 25 ℃; for 24h; Further byproducts given;

DOI:10.1246/bcsj.54.2728

Reference yield: 35.0%

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-galactopyranoside (76573-31-4) + 3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-α-D-glucopyranosyl bromide (3068-36-8) → Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8)

Guidance literature:

With tribenzylamine; silver perchlorate; In benzene; at 20 - 25 ℃; for 24h; Further byproducts given;

DOI:10.1246/bcsj.54.2728

Reference yield: 35.0%

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-galactopyranoside (76573-31-4) + 3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-α-D-glucopyranosyl bromide (3068-36-8) → Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) + Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2R,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8)

Guidance literature:

With tribenzylamine; silver perchlorate; In benzene; at 20 - 25 ℃; for 24h; Further byproducts given;

DOI:10.1246/bcsj.54.2728

upstream raw materials:

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-glucopyranoside

3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-α-D-glucopyranosyl bromide

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-galactopyranoside

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-mannopyranoside

Downstream raw materials:

(2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(3R,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6S)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6S)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol