(2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

Base Information

• Chemical Name: (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol
• CAS No.: 80035-28-5
• Molecular Formula: C₄₆H₄₅Cl₄N₃O₁₄
• Molecular Weight: 1005.69
• Mol file: 80035-28-5.mol

Synonyms:

Chemical Property of (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

There total 26 articles about (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(3R,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) → (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(3R,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol (80035-28-5,80081-10-3,80081-11-4,80081-12-5,80081-13-6,80081-14-7,80081-16-9,80081-17-0,80081-18-1)

Guidance literature:

With 1,4-dioxane; sodium methylate; In 1,4-dioxane; methanol; at 20 - 25 ℃; Yield given;

DOI:10.1246/bcsj.54.2728

Reference yield:

Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) → (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3R,4S,5S,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol (80035-28-5,80081-10-3,80081-11-4,80081-12-5,80081-13-6,80081-14-7,80081-16-9,80081-17-0,80081-18-1)

Guidance literature:

With sodium methylate; In methanol; at 20 - 25 ℃;

DOI:10.1246/bcsj.54.2728

Reference yield:

Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(2S,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester (74426-44-1,74464-69-0,74464-70-3,74464-71-4,74464-72-5,74464-73-6,74464-74-7,80081-07-8,80081-08-9,80081-09-0,80081-15-8) → (2R,3S,4R,5R,6R)-5-(2,4-Dinitro-phenylamino)-2-hydroxymethyl-6-[(2S,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol (80035-28-5,80081-10-3,80081-11-4,80081-12-5,80081-13-6,80081-14-7,80081-16-9,80081-17-0,80081-18-1)

Guidance literature:

With sodium methylate; In methanol; at 20 - 25 ℃;

DOI:10.1246/bcsj.54.2728

upstream raw materials:

Acetic acid (2R,3S,4R,5R,6R)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(3R,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester

2,3,4,6-tetra-O-(p-chlorobenzyl)-α-D-glucopyranoside

3,4,6-tri-O-acetyl-2-deoxy-2-(2,4-dinitroanilino)-α-D-glucopyranosyl bromide

Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-(2,4-dinitro-phenylamino)-6-[(3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-4-yl ester

Downstream raw materials:

(2R,3S,4R,5R,6R)-5-Amino-2-hydroxymethyl-6-[(2S,3R,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6R)-5-Amino-2-hydroxymethyl-6-[(2R,3R,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6S)-5-Amino-2-hydroxymethyl-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol

(2R,3S,4R,5R,6R)-5-Amino-2-hydroxymethyl-6-[(2R,3S,4S,5R,6R)-3,4,5-tris-(4-chloro-benzyloxy)-6-(4-chloro-benzyloxymethyl)-tetrahydro-pyran-2-yloxy]-tetrahydro-pyran-3,4-diol