methyl-phenyl-carbamoyl fluoride

Base Information

• Chemical Name: methyl-phenyl-carbamoyl fluoride
• CAS No.: 395-03-9
• Molecular Formula: C₈H₈FNO
• Molecular Weight: 153.156
• Mol file: 395-03-9.mol

Synonyms:

Chemical Property of methyl-phenyl-carbamoyl fluoride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl-phenyl-carbamoyl fluoride

There total 5 articles about methyl-phenyl-carbamoyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + N-methylaniline (100-61-8) → methyl-phenyl-carbamoyl fluoride (395-03-9)

Guidance literature:

With dmap; diethylamino-sulfur trifluoride; In acetonitrile; at 25 ℃; for 2h; under 760.051 Torr; Schlenk technique;

DOI:10.1002/anie.201907354

Reference yield:

N-methyl-N-(trifluoromethyl)aniline → methyl-phenyl-carbamoyl fluoride (395-03-9)

Guidance literature:

With water; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

DOI:10.1021/acs.jmedchem.0c01457

Reference yield:

Carbonyl fluoride (353-50-4) + N-methylaniline (100-61-8) → methyl-phenyl-carbamoyl fluoride (395-03-9)

Guidance literature:

With benzene;

upstream raw materials:

Carbonyl fluoride

N-methylaniline

fluoroformyl chloride

carbon dioxide