L-aspartylglycine dibenzylester

Base Information

• Chemical Name: L-aspartylglycine dibenzylester
• CAS No.: 101559-53-9
• Molecular Formula: C₂₀H₂₂N₂O₅
• Molecular Weight: 370.405
• Mol file: 101559-53-9.mol

Synonyms:

Chemical Property of L-aspartylglycine dibenzylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of L-aspartylglycine dibenzylester

There total 3 articles about L-aspartylglycine dibenzylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Gly-OBz (1738-68-7) → L-aspartylglycine dibenzylester (101559-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / DCC / dimethylformamide / Ambient temperature

2: TFA/anisole / 1 h

With methoxybenzene; dicyclohexyl-carbodiimide; trifluoroacetic acid; In N,N-dimethyl-formamide;

DOI:10.1248/cpb.33.3205

Reference yield:

Z(OMe)-Asp(OBzl)-ONp (53049-30-2) → L-aspartylglycine dibenzylester (101559-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / DCC / dimethylformamide / Ambient temperature

2: TFA/anisole / 1 h

With methoxybenzene; dicyclohexyl-carbodiimide; trifluoroacetic acid; In N,N-dimethyl-formamide;

DOI:10.1248/cpb.33.3205

Reference yield:

Z(OMe)-Asp(OBzl)-Gly-OBzl (101301-48-8) → L-aspartylglycine dibenzylester (101559-53-9)

Guidance literature:

With methoxybenzene; trifluoroacetic acid; for 1h;

DOI:10.1248/cpb.33.3205

upstream raw materials:

Z(OMe)-Asp(OBzl)-Gly-OBzl

Gly-OBz

Z(OMe)-Asp(OBzl)-ONp

Downstream raw materials:

Z-Ala-Ser-Asp(OBzl)-Gly-OBzl

Z-Lys(Z)-Ser-Asp(OBzl)-Gly-OBzl

Z(OMe)-His-Ala-Asp(OBzl)-Gly-OBzl

Z(OMe)-His-Ser(Bzl)-Asp(OBzl)-Gly-OBzl

Refernces