N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

Base Information

Chemical Name:N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide
CAS No.:106469-70-9
Molecular Formula:C₄₉H₄₃N₇O₇
Molecular Weight:841.923
Hs Code.:

N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

Synonyms:

Suppliers and Price of N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

There total 1 articles about N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 106502-49-2
C₂₅H₂₃N₂O₂⁽¹⁺⁾*2BF₄^(1-)*H⁽¹⁺⁾

: 6711-37-1
N⁶,N⁶-dibenzoyldeoxyadenosine

: 106469-70-9
N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

Guidance literature:: In N,N-dimethyl-formamide; for 0.166667h;
DOI:10.1021/jo00381a047

Reference yield:

: 106469-70-9
N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

: 106469-74-3
Dithiophosphoric acid O-[(2R,3S,5R)-5-(6-dibenzoylamino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-yl] ester S,S'-diphenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: mesitylenedisulfonyl chloride (MDS) / 0.17 h

2: 0.2 M dichloroacetic acid / CH₂Cl₂ / 0.01 h / 22 °C

With dichloro-acetic acid; 2,4,6-trimethyl-1,3-benzenedisulfonyl dichloride; In dichloromethane;
DOI:10.1021/jo00381a047

Reference yield:

: 106469-70-9
N-Benzoyl-N-(9-{(2R,4S,5R)-4-hydroxy-5-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide

: 106502-59-4
Thiophosphoric acid O-{(2R,3S,5R)-5-(6-dibenzoylamino-purin-9-yl)-2-[(3-imidazol-1-ylmethyl-phenyl)-bis-(4-methoxy-phenyl)-methoxymethyl]-tetrahydro-furan-3-yl} ester S-phenyl ester; compound with triethyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: mesitylenedisulfonyl chloride (MDS) / 0.17 h

2: 100 percent / phosphinic acid (PSA), pyridine / 0.17 h

With pyridine; 2,4,6-trimethyl-1,3-benzenedisulfonyl dichloride; hypophosphorous acid;
DOI:10.1021/jo00381a047