3-Ethyl-4-methylaniline

Base Information

• Chemical Name: 3-Ethyl-4-methylaniline
• CAS No.: 104715-64-2
• Molecular Formula: C9H13N
• Molecular Weight: 135.209
• DSSTox Substance ID: DTXSID00551805
• Wikidata: Q82431658
• Mol file: 104715-64-2.mol

Synonyms:3-ETHYL-4-METHYLANILINE;104715-64-2;Benzenamine, 3-ethyl-4-methyl-;SCHEMBL5953121;DTXSID00551805;KOPYKGJAQCIPTJ-UHFFFAOYSA-N;MFCD04112753;AKOS006293178;SY145003;CS-0224437;EN300-119406

Chemical Property of 3-Ethyl-4-methylaniline

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 135.104799419
• Heavy Atom Count: 10
• Complexity: 101

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC1=C(C=CC(=C1)N)C

Technology Process of 3-Ethyl-4-methylaniline

There total 7 articles about 3-Ethyl-4-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethyl-1-methyl-4-nitro-benzene (102877-97-4) → 1-amino-3-ethyl-4-methylbenzene (104715-64-2)

Guidance literature:

With ethanol; platinum; Hydrogenation;

DOI:10.1021/ja01534a030

Reference yield:

4-ethyl-5-methyl-2-nitro-aniline (103796-74-3) → 1-amino-3-ethyl-4-methylbenzene (104715-64-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous hydrochloric acid; sodium nitrite / anschliessend Behandeln mit Hypophosphorigsaeure

2: platinum; ethanol / Hydrogenation

With hydrogenchloride; ethanol; platinum; sodium nitrite;

DOI:10.1021/ja01534a030

Reference yield:

acetic acid-(4-ethyl-5-methyl-2-nitro-anilide) (103565-15-7) → 1-amino-3-ethyl-4-methylbenzene (104715-64-2)

Guidance literature:

Multi-step reaction with 3 steps

1: aq.-ethanolic NaOH

2: aqueous hydrochloric acid; sodium nitrite / anschliessend Behandeln mit Hypophosphorigsaeure

3: platinum; ethanol / Hydrogenation

With hydrogenchloride; sodium hydroxide; ethanol; platinum; sodium nitrite;

DOI:10.1021/ja01534a030

upstream raw materials:

2-ethyl-1-methyl-4-nitro-benzene

3-acetyl-4-methylaniline

hydrogenchloride

4-ethyl-5-methyl-2-nitro-aniline

Downstream raw materials:

3-ethyl-4-methylanilinouracil

6-(3-ethyl-4-methyl-phenylamino)-3-(2-methoxy-ethyl)-1H-pyrimidine-2,4-dione

6-(3-ethyl-4-methyl-phenylamino)-3-(3-methoxy-propyl)-1H-pyrimidine-2,4-dione

2-(3-ethyl-4-methylanilino)-9-[4-(1-morpholinyl)butyl]-6-oxo-3-deazapurine