6-fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydrotetraphene-7,12-diol

Base Information

Chemical Name:6-fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydrotetraphene-7,12-diol
CAS No.:104761-64-0
Molecular Formula:C20H21FO2
Molecular Weight:296.37900
Hs Code.:
Mol file:104761-64-0.mol

Synonyms:6-Fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydro-benzo[a]anthracen-12-ol;6-fluoro-1,2,3,4,7,12-hexahydro-7,12-dimethylbenz[a]anthracen-12-ol;

Suppliers and Price of 6-fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydrotetraphene-7,12-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydrotetraphene-7,12-diol

Chemical Property:

Vapor Pressure:4.89E-09mmHg at 25°C
PSA：20.23000
LogP:4.42550

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydrotetraphene-7,12-diol

There total 3 articles about 6-fluoro-7,12-dimethyl-1,2,3,4,7,12-hexahydrotetraphene-7,12-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104761-57-1
6-fluoro-2,3,4,7-tetrahydrobenz anthracen-12(H)-one

: 104761-59-3,104761-64-0,104761-66-2
trans-6-fluoro-1,2,3,4,7,12-hexahydro-7,12-dimethylbenz anthracene-7,12-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / K₂Cr₂O₇, glacial HOAc / 0.33 h / Heating

2: diethyl ether; benzene / 3 h / Heating

With potassium dichromate; acetic acid; In diethyl ether; benzene;
DOI:10.1021/jo00374a001

Reference yield:

: 75-16-1
methylmagnesium bromide

: 104761-58-2
6-fluoro-1,2,3,4-tetrahydrobenz anthracene-7,12-dione

: 104761-59-3,104761-64-0,104761-66-2
trans-6-fluoro-1,2,3,4,7,12-hexahydro-7,12-dimethylbenz anthracene-7,12-diol

: 104761-59-3
cis-6-fluoro-1,2,3,4,7,12-hexahydro-7,12-dimethylbenz anthracene-7,12-diol

Guidance literature:: In diethyl ether; benzene; for 3h; Yield given. Yields of byproduct given; Heating;
DOI:10.1021/jo00374a001

Reference yield:

: 75-16-1
methylmagnesium bromide

: 104761-63-9
6-fluoro-2,3,4,7-tetrahydro-7-methylbenz anthracen-12(1H)-one

: 104761-60-6
6-fluoro-1,2,3,4,7,12-hexahydro-7-methyl-12-methylenebenz anthracene

: 104761-64-0
6-fluoro-1,2,3,4,7,12-hexahydro-7,12-dimethylbenz anthracen-12-ol

Guidance literature:: With hydrogenchloride; Yield given. Multistep reaction. Yields of byproduct given; 1.) Et₂O, reflux, 3 h, 2.) Et₂O, benzene, reflux, 4 h;
DOI:10.1021/jo00374a001