Technology Process of C27H28N2O
There total 2 articles about C27H28N2O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
bis(η3-allyl-μ-chloropalladium(II)); (R)-dicycloheptyl(4'-(trimethylsilyl)-[1,1'-binaphthalen]-2-yl)phosphine; sodium t-butanolate;
In
cyclohexane;
at 20 ℃;
for 2h;
enantioselective reaction;
Sealed tube;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/ja501560x
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dichloromethane; cyclohexane / 2 h / 20 °C / Molecular sieve; Schlenk technique; Inert atmosphere; Cooling with ice
2: (R)-dicycloheptyl(4'-(trimethylsilyl)-[1,1'-binaphthalen]-2-yl)phosphine; bis(η3-allyl-μ-chloropalladium(II)); sodium t-butanolate / cyclohexane / 2 h / 20 °C / Sealed tube; Schlenk technique; Inert atmosphere
With
bis(η3-allyl-μ-chloropalladium(II)); (R)-dicycloheptyl(4'-(trimethylsilyl)-[1,1'-binaphthalen]-2-yl)phosphine; sodium t-butanolate;
In
dichloromethane; cyclohexane;
DOI:10.1021/ja501560x
- Guidance literature:
-
With
sodium tetrahydroborate; acetic acid;
In
dichloromethane;
at 20 ℃;
for 1h;
Cooling with ice;
DOI:10.1021/ja501560x