9-Aminofluorene

Base Information

• Chemical Name: 9-Aminofluorene
• CAS No.: 525-03-1
• Molecular Formula: C13H11N
• Molecular Weight: 181.237
• Hs Code.: 2921499090
• UNII: 4NHO2K4K5B
• DSSTox Substance ID: DTXSID90200496
• Nikkaji Number: J69.708G
• Wikidata: Q27260248
• Mol file: 525-03-1.mol

Synonyms:9-Aminofluorene;9AmFL cpd

Chemical Property of 9-Aminofluorene

Chemical Property:

• Melting Point: 64℃
• Refractive Index: 1.6118 (estimate)
• Boiling Point: 331.1 °C at 760 mmHg
• PKA: 8.18±0.20(Predicted)
• Flash Point: 168.1 °C
• PSA: 26.02000
• Density: 1.162 g/cm³
• LogP: 3.41540
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 181.089149355
• Heavy Atom Count: 14
• Complexity: 191

Purity/Quality:

99%, ^*data from raw suppliers

9H-Fluoren-9-amine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)N

Technology Process of 9-Aminofluorene

There total 13 articles about 9-Aminofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

fluorenone tosylhydrazone anion → p-toluene sulfinic acid (536-57-2) + fluorenone imine (4440-33-9) + 9-aminofluorene (525-03-1) + N'-(9H-fluoren-9-ylidene)-4-methylbenzenesulfonohydrazide (52341-51-2) + toluene-4-sulfonamide (70-55-3) + fluoren-9-ylidene-hydrazine (13629-22-6)

Guidance literature:

With tetrabutylammonium perchlorate; In N,N-dimethyl-formamide; at 22 ℃; Product distribution; electrolytic reduction at a platinum gauze electrode; also addition of proton donors;

DOI:10.1021/jo00363a027

Reference yield: 51.5%

9-fluorenone triphenylphosphazine (751-35-9) → di-fluoren-9-ylidene-hydrazine (2071-44-5) + 9-aminofluorene (525-03-1) + fluoren-9-ylidene-hydrazine (13629-22-6) + diphenylphosphane (829-85-6)

Guidance literature:

With sodium; In tetrahydrofuran; for 0.75h;

Reference yield: 8.2%

9-fluorenone (486-25-9,952573-42-1) + acetic acid (64-19-7,77671-22-8) + benzylamine (100-46-9) → 9-aminofluorene (525-03-1) + N-(9H-fluoren-9-yl)acetamide (5424-77-1) + benzaldehyde (100-52-7)

Guidance literature:

In toluene; for 101h; Heating;

DOI:10.1021/jo01310a049

upstream raw materials:

9H-fluoren-9-yl bromide

sodium acetate

potassium phtalimide

nitrobenzene

Downstream raw materials:

9-fluorenone

9-Fluorenol

9,9'-bifluorenyl

benzaldehyde 9-fluorenyl imine