2-(4-Chlorophenyl)-5-(1-(5-tetrazolyl)ethyl)benzoxazole

Base Information

• Chemical Name: 2-(4-Chlorophenyl)-5-(1-(5-tetrazolyl)ethyl)benzoxazole
• CAS No.: 54785-35-2
• Molecular Formula: C16H12 Cl N5 O
• Molecular Weight: 325.7524
• DSSTox Substance ID: DTXSID60970114
• Nikkaji Number: J67.907K

Synonyms:54785-35-2;BRN 1089548;2-(4-Chlorophenyl)-5-(1-(5-tetrazolyl)ethyl)benzoxazole;BENZOXAZOLE, 2-(4-CHLOROPHENYL)-5-(1-(5-TETRAZOLYL)ETHYL)-;2-(4-chlorophenyl)-5-[1-(2H-tetrazol-5-yl)ethyl]-1,3-benzoxazole;C16H12ClN5O;C16-H12-Cl-N5-O;DTXSID60970114;LS-42173;2-(4-Chlorophenyl)-5-[1-(1H-tetrazol-5-yl)ethyl]benzoxazole;Benzoxazole, 2-(4-chlorophenyl)-5-[1-(1H-tetrazol-5-yl)ethyl]-

Chemical Property of 2-(4-Chlorophenyl)-5-(1-(5-tetrazolyl)ethyl)benzoxazole

Chemical Property:

• Vapor Pressure: 1.06E-10mmHg at 25°C
• Boiling Point: 514.6°C at 760 mmHg
• Flash Point: 265°C
• Density: 1.407g/cm³
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 325.0730377
• Heavy Atom Count: 23
• Complexity: 406

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC2=C(C=C1)OC(=N2)C3=CC=C(C=C3)Cl)C4=NNN=N4

Technology Process of 2-(4-Chlorophenyl)-5-(1-(5-tetrazolyl)ethyl)benzoxazole

There total 7 articles about 2-(4-Chlorophenyl)-5-(1-(5-tetrazolyl)ethyl)benzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-p-chlorophenyl-5-benzoxazolyl)propionitrile (51234-36-7,67146-21-8) → 2-(4-chloro-phenyl)-5-[1-(1H-tetrazol-5-yl)-ethyl]-benzooxazole (54785-35-2)

Guidance literature:

With sodium azide; ammonium chloride; In N,N-dimethyl-formamide; at 125 ℃; for 24h;

DOI:10.1021/jm00235a012

Reference yield:

2-(4-hydroxyphenyl)propanenitrile (21850-61-3) → 2-(4-chloro-phenyl)-5-[1-(1H-tetrazol-5-yl)-ethyl]-benzooxazole (54785-35-2)

Guidance literature:

Multi-step reaction with 4 steps

1: HNO₃ / acetic acid

2: SnCl₂, aq. HCl / ethanol

3: Py

4: NaN₃, NH₄Cl / dimethylformamide / 24 h / 125 °C

With pyridine; hydrogenchloride; sodium azide; nitric acid; ammonium chloride; tin(ll) chloride; In ethanol; acetic acid; N,N-dimethyl-formamide;

DOI:10.1021/jm00235a012

Reference yield:

3-nitro-4-hydroxyphenyl-α-methyl-acetonitrile (51234-22-1,66934-21-2) → 2-(4-chloro-phenyl)-5-[1-(1H-tetrazol-5-yl)-ethyl]-benzooxazole (54785-35-2)

Guidance literature:

Multi-step reaction with 3 steps

1: SnCl₂, aq. HCl / ethanol

2: Py

3: NaN₃, NH₄Cl / dimethylformamide / 24 h / 125 °C

With pyridine; hydrogenchloride; sodium azide; ammonium chloride; tin(ll) chloride; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00235a012

upstream raw materials:

2-(2-p-chlorophenyl-5-benzoxazolyl)propionitrile

2-(4-hydroxyphenyl)propanenitrile

3-nitro-4-hydroxyphenyl-α-methyl-acetonitrile

2-(3-amino-4-hydroxyphenyl)-propionitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 54785-35-2 2-(4-chlorophenyl)-5-[1-(2H-tetrazol-5-yl)ethyl]-1,3-benzoxazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send