o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol

Base Information

• Chemical Name: o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol
• CAS No.: 81758-03-4
• Molecular Formula: C₂₆H₃₅NO₄
• Molecular Weight: 425.568
• Mol file: 81758-03-4.mol

Synonyms:

Chemical Property of o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol

There total 2 articles about o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2E,7E,11E)-7,11-Dimethyl-4-isopropylcyclotetradeca-2,7,11-trien-1-one (57283-41-7) → o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol (81758-03-4,134236-58-1,134236-59-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.15 g / lithium tetrahydroaluminate / diethyl ether / 0.17 h / Ambient temperature

2: pyridine / 0.17 h / 70 - 80 °C

With lithium aluminium tetrahydride; In pyridine; diethyl ether;

DOI:10.1007/BF00574371

Reference yield:

18-nor-4S-cembra-2E,7E,11E-trien-4-ol (57283-40-6,81800-55-7,134236-56-9,134236-57-0) + 2-nitrobenzyl chloride (610-14-0) → o-nitrobenzoate of 18-nor-4S-cembra-2E,7E,11E-trien-4-ol (81758-03-4,134236-58-1,134236-59-2)

Guidance literature:

In pyridine; at 70 - 80 ℃; for 0.166667h;

DOI:10.1007/BF00574371

upstream raw materials:

18-nor-4S-cembra-2E,7E,11E-trien-4-ol

2-nitrobenzyl chloride

(2E,7E,11E)-7,11-Dimethyl-4-isopropylcyclotetradeca-2,7,11-trien-1-one