1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol

Base Information

• Chemical Name: 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol
• CAS No.: 87657-77-0
• Molecular Formula: C₂₀H₂₆O₃
• Molecular Weight: 314.425
• Mol file: 87657-77-0.mol

Synonyms:

Chemical Property of 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol

Chemical Property:

Purity/Quality:

≥98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol

There total 11 articles about 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-phenylpropenal (14371-10-9) → 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol (87657-77-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 10percent aq. NaOH / 3 h / Ambient temperature

2: H₂ / 5percent Pd/C / CHCl₃ / 9 h

3: 80 percent / acetic acid/pyrrolidine / diethyl ether

4: 98 percent / H₂ / 5percent palladium-carbon / benzene

5: NaBH₄ / methanol

With pyrrolidine; sodium hydroxide; sodium tetrahydroborate; hydrogen; acetic acid; palladium on activated charcoal; In methanol; diethyl ether; chloroform; benzene;

DOI:10.1248/cpb.31.2491

Reference yield:

1-phenyl-5-hexanone (14171-89-2) → 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol (87657-77-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / acetic acid/pyrrolidine / diethyl ether

2: 98 percent / H₂ / 5percent palladium-carbon / benzene

3: NaBH₄ / methanol

With pyrrolidine; sodium tetrahydroborate; hydrogen; acetic acid; palladium on activated charcoal; In methanol; diethyl ether; benzene;

DOI:10.1248/cpb.31.2491

Reference yield:

vanillin (121-33-5,8014-42-4) → 1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-3-heptanol (87657-77-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / acetic acid/pyrrolidine / diethyl ether

2: 98 percent / H₂ / 5percent palladium-carbon / benzene

3: NaBH₄ / methanol

With pyrrolidine; sodium tetrahydroborate; hydrogen; acetic acid; palladium on activated charcoal; In methanol; diethyl ether; benzene;

DOI:10.1248/cpb.31.2491

upstream raw materials:

(E)-3-phenylpropenal

1-phenyl-5-hexanone

vanillin

1-(3-methoxy-4-hydroxyphenyl)-7-phenylhept-1-en-3-one