N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

Base Information

Chemical Name:N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
CAS No.:115931-01-6
Molecular Formula:C15H11 N5 O
Molecular Weight:277.285
Hs Code.:
UNII:C6S8C8MX0L
DSSTox Substance ID:DTXSID90433888
Nikkaji Number:J579.777B
Wikidata:Q82248157
ChEMBL ID:CHEMBL3526260
Mol file:115931-01-6.mol

Synonyms:115931-01-6;N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide;Zaleplon desethyl;N-Desesethylzaleplon;C6S8C8MX0L;CL-284859;UNII-C6S8C8MX0L;Acetamide, N-(3-(3-cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-;Pyrazolo(1,5-a)pyrimidine, acetamide deriv.;N-(3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl)acetamide;Acetamide, N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-;N-(3-(3-CYANOPYRAZOLO(1,5-A)PYRIMIDIN-7-YL)PHENYL)ACETAMIDE;N-(3-{3-CYANOPYRAZOLO[1,5-A]PYRIMIDIN-7-YL}PHENYL)ACETAMIDE;SCHEMBL5275982;CHEMBL3526260;DTXSID90433888;HGCZTXQJFDPOKK-UHFFFAOYSA-N;AKOS027446685;DESETHYLZALEPLON [USP IMPURITY];FT-0665322;J-003338;N-[3-(3-cyano-pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

Suppliers and Price of N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
10mg
$ 155.00

Biosynth Carbosynth
N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
25 mg
$ 413.00

Biosynth Carbosynth
N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
10 mg
$ 227.20

Biosynth Carbosynth
N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
5 mg
$ 124.90

Biosynth Carbosynth
N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
100 mg
$ 1365.00

Biosynth Carbosynth
N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide
50 mg
$ 751.00

American Custom Chemicals Corporation
N-(3-(3-CYANOPYRAZOLO(1,5-A)PYRIMIDIN-7-YL)PHENYL)ACETAMIDE 95.00%
100MG
$ 1732.50

American Custom Chemicals Corporation
N-(3-(3-CYANOPYRAZOLO(1,5-A)PYRIMIDIN-7-YL)PHENYL)ACETAMIDE 95.00%
10MG
$ 721.88

Total 3 raw suppliers

Chemical Property of N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

Chemical Property:

Melting Point:256-260 °C
PKA:14.66±0.70(Predicted)
PSA：86.57000
Density:1.342g/cm³
LogP:2.87588
Storage Temp.:Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:277.09635999
Heavy Atom Count:21
Complexity:445

Purity/Quality:

95% ^*data from raw suppliers

N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=CC(=C1)C2=CC=NC3=C(C=NN23)C#N
Uses A metabolite of Zaleplon

Technology Process of N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

There total 9 articles about N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 108-24-7
acetic anhydride

: CL 314475

: 115931-01-6
N-[3-(3-cyano-pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

Guidance literature:: With pyridine; at 20 ℃; for 20h;
DOI:10.1002/jlcr.1484

Reference yield: 83.0%

: 64-19-7,77671-22-8
acetic acid

: 115930-99-9
7-(3-nitrophenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonitrile

: 115931-01-6
N-[3-(3-cyano-pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]acetamide

Guidance literature:: acetic acid; With iron; at 120 ℃; for 0.166667h;

7-(3-nitrophenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonitrile; at 120 ℃; for 4h;