(4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate

Base Information

• Chemical Name: (4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate
• CAS No.: 1215019-57-0
• Molecular Formula: C₄₇H₅₇N₈O₈P
• Molecular Weight: 892.992

Synonyms:

Chemical Property of (4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Useful:

Technology Process of (4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate

There total 1 articles about (4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

4-methoxy-1-oxido-2-pyridylmethanol (64364-95-0) + C40H50N7O6P (1215019-58-1) → (4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N6-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate (1215019-57-0)

Guidance literature:

With pyridine; 2,4,6-triisopropylphenylsulfonyl chloride; at 20 ℃;

DOI:10.1135/cccc2009022

upstream raw materials:

4-methoxy-1-oxido-2-pyridylmethanol

C₄₀H₅₀N₇O₆P

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