64364-95-0

Basic information

• Product Name: 2-Pyridinemethanol, 4-methoxy-, 1-oxide (9CI)
• Synonyms: 2-Pyridinemethanol, 4-methoxy-, 1-oxide (9CI);2-Pyridinemethanol, 4-methoxy-, 1-oxide
• CAS NO: 64364-95-0
• Molecular Formula: C₇H₉NO₃
• Molecular Weight: 155.15126
• Product Categories: ALDEHYDE
• Mol File: 64364-95-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinemethanol, 4-methoxy-, 1-oxide (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinemethanol, 4-methoxy-, 1-oxide (9CI)(64364-95-0)
• EPA Substance Registry System: 2-Pyridinemethanol, 4-methoxy-, 1-oxide (9CI)(64364-95-0)

Safety Data

• Hazardous Substances Data: 64364-95-0(Hazardous Substances Data)

Usage

General Description

"2-Pyridinemethanol, 4-methoxy-, 1-oxide (9CI)" is a specific chemical compound that belongs to the family of Pyridines and derivatives. This chemical is particularly known for its complex structure and properties. The primary characteristic of the chemical lies in its methoxy group attached to the fourth carbon atom and its oxide attached to the first carbon atom on the pyridine ring. It is identified by the Chemical Abstracts Service (CAS) number . Commonly used in the field of chemistry for various applications, its physical and chemical properties, such as melting point, boiling point, density and molecular weight, can vary based on conditions.

Upstream product

• 5470-66-6 2-methyl-4-nitropyridine N-oxide 
• 931-19-1 2-methylpyridine N-oxide 
• 76133-00-1 2-formyl-4-nitropyridine ethylene acetal 1-oxide 
• 77345-73-4 4-methoxy-2-formylpyridine ethylene acetal 1-oxide 
• 65227-58-9 2-formyl-4-nitropyridine 1-oxide 
• 124-41-4 sodium methylate 
• 77345-71-2 4-nitro-2-pyridylmethanol 1-oxide 
• 77345-69-8 2-formyl-4-methoxypyridine-1-oxide 

Downstream Products

• 184159-50-0 ({{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-[2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-methyl)-phosphonic acid 4-methoxy-1-oxy-pyridin-2-ylmethyl ester phenyl ester 
• 184159-51-1 [([2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-{2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-amino)-methyl]-phosphonic acid 4-methoxy-1-oxy-pyridin-2-ylmethyl ester phenyl ester 
• 250649-66-2 4-Methoxy-1-oxido-2-picolyl o-chlorophenyl[1-(3`-O-tert-butyldiphenylsilyl-2`,5`,6`-trideoxy-β-D-erythro-hexofuranosyl)-4-N-isobutyrylcytidin-6`-yl]phosphonate 
• 250650-36-3 4-Methoxy-1-oxido-2-picolyl phenyl[9-(3`-O-tert-butyldiphenylsilyl-2`,5`,6`-trideoxy-β-D-erythro-hexofuranosyl)-6-N-benzoyladenin-6`-yl]phosphonate 
• 250650-32-9 4-Methoxy-1-oxido-2-picolyl phenyl [9-(3`-O-tert-butyldiphenylsilyl-2`,5`,6`-trideoxy-β-D-erythro-hexofuranosyl)-2-N-isobutyrylguanin-6`-yl]phosphonate 
• 1215019-57-0 (4-methoxy-1-oxido-2-pyridyl)methyl (3R,4R)-3-{[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}methylphosphonate 
• 1215019-61-6 (4-methoxy-1-oxido-2-pyridyl)methyl 2-{(3R,4R)-3-[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}ethylphosphonate 
• 1215019-65-0 (4-methoxy-1-oxido-2-pyridyl)methyl 2-{(3R,4R)-3-[N₆-(dibutylamino)methyleneadenin-9-yl]-4-(4,4'-dimethoxytrityl)oxypyrrolidin-1-yl}-2-oxoethylphosphonate 

Relevant articles and documents

Large-scale synthesis of a key catalytic reagent for phosphorus protection in building blocks for isopolar phosphonate oligonucleotide preparation

A simple procedure for the large-scale synthesis of 4-methoxy-2-pyridinemethanol 1-oxide (5), a key compound in modern triester synthesis of oligonucleotides, employing Buechi R 152 evaporator as a reaction apparatus was elaborated. Two crucial reaction steps, both strongly exothermic, were satisfactorily handled. Our procedure provides a high-purity, light-and heat-stable product in a satisfactory yield.