C₄H₆O₆*C₉H₁₁N

Base Information

• Chemical Name: C₄H₆O₆*C₉H₁₁N
• CAS No.: 220241-67-8
• Molecular Formula: C₄H₆O₆*C₉H₁₁N
• Molecular Weight: 283.281
• Mol file: 220241-67-8.mol

Synonyms:

Chemical Property of C₄H₆O₆*C₉H₁₁N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄H₆O₆*C₉H₁₁N

There total 1 articles about C₄H₆O₆*C₉H₁₁N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

L-Tartaric acid (87-69-4,138508-61-9) + trans-2-phenylcyclopropylamine (155-09-9) → C4H6O6*C9H11N (220241-67-8)

Guidance literature:

In ethanol; Heating;

DOI:10.1016/j.bmcl.2011.06.023

Reference yield:

C4H6O6*C9H11N (220241-67-8) → C21H22Cl2N4O2 (1329683-24-0)

Guidance literature:

Multi-step reaction with 7 steps

1: sodium hydroxide / diethyl ether; water

2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide

3: trifluoroacetic acid / dichloromethane

4: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

5: palladium on carbon; hydrogen / methanol

6: N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane

7: hydrogenchloride / 1,4-dioxane; water

With hydrogenchloride; palladium on carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; sodium hydroxide; In 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.06.023

Reference yield:

C4H6O6*C9H11N (220241-67-8) → C27H33N3O5

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / diethyl ether; water

2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide

With N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; In diethyl ether; water; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2011.06.023

upstream raw materials:

L-Tartaric acid

trans-2-phenylcyclopropylamine

Downstream raw materials:

C₂₃H₂₃N₃O₄

C₁₅H₁₇N₃O₂

C₂₂H₂₀Cl₂N₄O₃

C₂₁H₂₂Cl₂N₄O₂