C₂₅H₂₉N₃O₂

Base Information

• Chemical Name: C₂₅H₂₉N₃O₂
• CAS No.: 870544-77-7
• Molecular Formula: C₂₅H₂₉N₃O₂
• Molecular Weight: 403.524
• Mol file: 870544-77-7.mol

Synonyms:

Chemical Property of C₂₅H₂₉N₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₉N₃O₂

There total 5 articles about C₂₅H₂₉N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

4-tert-Butylaniline (769-92-6) + C15H14N2O2 → C25H29N3O2 (870544-77-7)

Guidance literature:

In toluene; at 80 ℃; for 1.5h; Inert atmosphere;

DOI:10.1021/jm301708u

Reference yield:

2-(1-methylethyl)phenol (88-69-7) → C25H29N3O2 (870544-77-7)

Guidance literature:

Multi-step reaction with 4 steps

1: caesium carbonate / N,N-dimethyl-formamide / 18 h / 80 °C / Inert atmosphere

2: zinc; ammonium chloride / ethanol; ethyl acetate / 20 °C / Inert atmosphere

3: trichloromethyl chloroformate; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 0.75 h / 0 °C / Inert atmosphere

4: toluene / 1.5 h / 80 °C / Inert atmosphere

With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; ammonium chloride; caesium carbonate; zinc; trichloromethyl chloroformate; In ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; toluene;

DOI:10.1021/jm301708u

Reference yield:

C14H14N2O3 (1119225-31-8) → C25H29N3O2 (870544-77-7)

Guidance literature:

Multi-step reaction with 3 steps

1: zinc; ammonium chloride / ethanol; ethyl acetate / 20 °C / Inert atmosphere

2: trichloromethyl chloroformate; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 0.75 h / 0 °C / Inert atmosphere

3: toluene / 1.5 h / 80 °C / Inert atmosphere

With N,N,N',N'-tetramethyl-1,8-diaminonaphthalene; ammonium chloride; zinc; trichloromethyl chloroformate; In ethanol; dichloromethane; ethyl acetate; toluene;

DOI:10.1021/jm301708u

upstream raw materials:

4-tert-Butylaniline

2-(1-methylethyl)phenol

C₁₄H₁₄N₂O₃

2-Chloro-3-nitropyridine