prop-2-yn-1-yl 2-(4-fluorophenyl)-2-oxoacetate

Base Information

• Chemical Name: prop-2-yn-1-yl 2-(4-fluorophenyl)-2-oxoacetate
• CAS No.: 1357932-30-9
• Molecular Formula: C₁₁H₇FO₃
• Molecular Weight: 206.173
• Mol file: 1357932-30-9.mol

Synonyms:

Chemical Property of prop-2-yn-1-yl 2-(4-fluorophenyl)-2-oxoacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of prop-2-yn-1-yl 2-(4-fluorophenyl)-2-oxoacetate

There total 1 articles about prop-2-yn-1-yl 2-(4-fluorophenyl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

α,α-Dibromo-4'-fluoroacetophenone (7542-64-5) + propargyl alcohol (107-19-7) → prop-2-yn-1-yl 2-(4-fluorophenyl)-2-oxoacetate (1357932-30-9)

Guidance literature:

α,α-Dibromo-4'-fluoroacetophenone; With dimethyl sulfoxide; at 70 - 75 ℃; Inert atmosphere;

propargyl alcohol; at 25 - 30 ℃; Inert atmosphere;

DOI:10.1055/s-0031-1289647

upstream raw materials:

α,α-Dibromo-4'-fluoroacetophenone

propargyl alcohol

Refernces