AJ₃₄

Base Information

• Chemical Name: AJ₃₄
• CAS No.: 1415548-66-1
• Molecular Formula: C₃₁H₅₁FN₄O₇S
• Molecular Weight: 642.833
• Mol file: 1415548-66-1.mol

Synonyms:

Chemical Property of AJ₃₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of AJ₃₄

There total 7 articles about AJ₃₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H46FN3O7S (1415548-63-8) → AJ34 (1415548-66-1)

Guidance literature:

Multi-step reaction with 4 steps

1: dichloromethane / 0.25 h / 20 °C

2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

3: dichloromethane / 0.25 h / 20 °C

4: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1021/jm301443r

Reference yield:

C22H35FN2O6S (1415548-62-7) → AJ34 (1415548-66-1)

Guidance literature:

Multi-step reaction with 6 steps

1: dichloromethane / 0.25 h / 20 °C

2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

3: dichloromethane / 0.25 h / 20 °C

4: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

5: dichloromethane / 0.25 h / 20 °C

6: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1021/jm301443r

Reference yield:

Cbz-Leu-ψ[CH2SO2]-F (1169199-23-8) → AJ34 (1415548-66-1)

Guidance literature:

Multi-step reaction with 8 steps

1.1: hydrogen bromide; acetic acid / 0.5 h / 20 °C

1.2: Dowex-Cl / 0.08 h / 20 °C

2.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

3.1: dichloromethane / 0.25 h / 20 °C

4.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

5.1: dichloromethane / 0.25 h / 20 °C

6.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

7.1: dichloromethane / 0.25 h / 20 °C

8.1: dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere

With hydrogen bromide; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; acetic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1021/jm301443r

upstream raw materials:

C₂₂H₃₅FN₂O₆S

C₂₈H₄₆FN₃O₇S

Cbz-Leu-ψ[CH2SO2]-F

C₆H₁₄FNO₂S