2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid

Base Information

Chemical Name:2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid
CAS No.:78160-06-2
Molecular Formula:C₁₄H₁₁NO₅S
Molecular Weight:305.311
Hs Code.:
DSSTox Substance ID:DTXSID501255148

Synonyms:2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid;SCHEMBL6932354;DTXSID501255148;AKOS009002010;78160-06-2

Suppliers and Price of 2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:305.03579362
Heavy Atom Count:21
Complexity:378

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)SC2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O

Technology Process of 2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid

There total 1 articles about 2-[(4-Methoxyphenyl)thio]-5-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 696-63-9
4-Methoxybenzenethiol

: 2516-96-3
2-chloro-5-nitrobenzoic acid

: 78160-06-2
2-carboxy-4-nitro-4'-methoxydiphenyl sulphide

Guidance literature:: With potassium carbonate; Yield given. Multistep reaction; 1) water, methanol, reflux, 2) methanol, 10 h, reflux;

Reference yield: 85.0%

: 78160-06-2
2-carboxy-4-nitro-4'-methoxydiphenyl sulphide

: 78160-09-5
5-Amino-2-(4-methoxy-phenylsulfanyl)-benzoic acid

Guidance literature:: With hydrogenchloride; iron; 1) water, 90-95 deg C, 2) methanol, reflux, 3-4 h;

Reference yield:

: 78160-06-2
2-carboxy-4-nitro-4'-methoxydiphenyl sulphide

: 78160-50-6
2-(4-Methoxy-phenylsulfanyl)-5-(3-phenyl-thioureido)-benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / iron powder, conc. HCl / 1) water, 90-95 deg C, 2) methanol, reflux, 3-4 h

2: 82 percent / NaHCO₃ / H₂O; methanol / Heating

With hydrogenchloride; iron; sodium hydrogencarbonate; In methanol; water;