2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione

Base Information

• Chemical Name: 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione
• CAS No.: 129189-17-9
• Molecular Formula: C₄₈H₄₉NO₁₃
• Molecular Weight: 847.916

Synonyms:

Chemical Property of 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione

There total 5 articles about 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (2R,3S,4S,5R,6R)-5-acetoxy-4-allyloxy-2-allyloxymethyl-6-chloro-tetrahydro-pyran-3-yl ester (110426-17-0) → 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione (129189-17-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / silver triflate

2: 91 percent / LiOH/H₂O₂

3: 90 percent / benzylation

4: Wilkinson's catalyst

With lithium hydroxide; dihydrogen peroxide; silver trifluoromethanesulfonate; Wilkinson's catalyst;

DOI:10.1016/S0040-4039(01)80741-3

Reference yield:

allyl 3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranoside (125946-67-0) → 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione (129189-17-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / silver triflate

2: 91 percent / LiOH/H₂O₂

3: 90 percent / benzylation

4: Wilkinson's catalyst

With lithium hydroxide; dihydrogen peroxide; silver trifluoromethanesulfonate; Wilkinson's catalyst;

DOI:10.1016/S0040-4039(01)80741-3

Reference yield:

allyl O-(2,4-di-O-acetyl-3,6-di-O-allyl-β-D-galactopyranosyl)-(1->4)-3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranoside (129162-99-8) → 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione (129189-17-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 91 percent / LiOH/H₂O₂

2: 90 percent / benzylation

3: Wilkinson's catalyst

With lithium hydroxide; dihydrogen peroxide; Wilkinson's catalyst;

DOI:10.1016/S0040-4039(01)80741-3

upstream raw materials:

allyl O-(3,6-di-O-allyl-2,4-di-O-benzyl-β-D-galactopyranosyl)-(1->4)-3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranoside

Acetic acid (2R,3S,4S,5R,6R)-5-acetoxy-4-allyloxy-2-allyloxymethyl-6-chloro-tetrahydro-pyran-3-yl ester

allyl 3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranoside

allyl O-(3,6-di-O-allyl-β-D-galactopyranosyl)-(1->4)-3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranoside

Downstream raw materials:

Acetic acid (2R,3S,4S,5R,6S)-2-acetoxymethyl-3,5-bis-benzyloxy-6-[(2R,3S,4R,5R,6R)-4-benzyloxy-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-6-hydroxy-2-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-4-yl ester

O-(3,6-di-O-acetyl-2,4-di-O-benzyl-β-D-galactopyranosyl)-(1->4)-3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranosyl trichloroacetimidate

O-(3,6-di-O-acetyl-2,4-di-O-benzyl-β-D-galactopyranosyl)-(1->4)-3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-β-D-glucopyranosyl acetate

O-(3,6-di-O-acetyl-2,4-di-O-benzyl-β-D-galactopyranosyl)-(1->4)-3-O-benzyl-2-deoxy-6-O-p-methoxyphenyl-2-phthalimido-α-D-glucopyranosyl acetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 129189-17-9 2-[(2R,3R,4R,5S,6R)-4-Benzyloxy-5-((2S,3R,4S,5R,6R)-3,5-bis-benzyloxy-4-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-isoindole-1,3-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send